An in vitro screening method for DNA cytosine-C5-Methylase inhibitor

Natural Product Letters

Volumn 16, Issue 1, 2002, Pages 25-27

  Tamura, Takashi ^a   Kataoka, Atsushi ^a   Shu, Li Yin ^a   Ashida, Akihiko ^a   Tanaka, Hidehiko ^a   Inagaki, Kenji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

DNA methylase; S Adenosyl L methionine; Sinefungin

Indexed keywords

DNA; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE 5) METHYLTRANSFERASE INHIBITOR; ENDONUCLEASE; ENZYME INHIBITOR; S ADENOSYLMETHIONINE; SINEFUNGIN; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; CARCINOGENESIS; CONTROLLED STUDY; DNA METHYLATION; DRUG SCREENING; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENOME IMPRINTING; IN VITRO STUDY; MICROORGANISM; NONHUMAN; PROMOTER REGION; X CHROMOSOME INACTIVATION;

ADENOSINE; BACTERIA; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA RESTRICTION-MODIFICATION ENZYMES; ELECTROPHORESIS, AGAR GEL; ENZYME INHIBITORS; ESCHERICHIA COLI; S-ADENOSYLMETHIONINE; SEQUENCE HOMOLOGY, NUCLEIC ACID; SITE-SPECIFIC DNA METHYLTRANSFERASE (CYTOSINE-SPECIFIC); X CHROMOSOME;

EID: 0036107952     PISSN: 10575634     EISSN: None     Source Type: Journal    
DOI: 10.1080/1057563029001/4809     Document Type: Article

References (4)

1. Regulation and function of DNA methylation in vertebrates
2. CpG islands
3. A9145, a new adenine-containing antifungal antibiotic. I. Discovery and isolation (1973)
4. Effects of sinefungin and S-adenosylhomocysteine on DNA and protein methyltransferases from Streptomyces and other bacteria