High overexpression of the human α-galactosidase a gene driven by its promoter in transgenic mice: Implications for the treatment of fabry disease

Journal of Investigative Medicine

Volumn 50, Issue 3, 2002, Pages 185-192

  Ashley, Grace A ^a   Desnick, Robert J ^a   Gordon, Ronald E ^a   Gordon, Jon W ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Fabry disease; Gene regulation; Promoter sequences; Transgenic mice; galactosidase A

Indexed keywords

ALPHA GALACTOSIDASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ENHANCER REGION; ENZYME ACTIVITY; FABRY DISEASE; GENE CONSTRUCT; GENE CONTROL; GENE OVEREXPRESSION; GENE SEQUENCE; GENE THERAPY; GENETIC CODE; GENOTYPE; HOUSEKEEPING GENE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROMOTER REGION; TRANSGENE; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS;

EID: 0036097856     PISSN: 17088267     EISSN: None     Source Type: Journal    
DOI: 10.2310/6650.2002.33432     Document Type: Article

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