Tuning of T cell clone size and activation threshold by control of CD25 expression through mitogen-activated protein kinase pathways

International Archives of Allergy and Immunology

Volumn 127, Issue 4, 2002, Pages 322-332

  Bitegye, Christina ^a   Hannier, Sigrid ^a   Guérif, Stéphane ^a   Valitutti, Salvatore ^b   Demotz, Stéphane ^a,c  

^a PFIZER INC   (United States)

^b CHU PURPAN   (France)

^c RMF Dictagene   (Switzerland)

Author keywords

CD25; MAPK; T cell receptor; T helper 1 and 2 lymphocytes

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 NITROPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CD2 ANTIGEN; CD3 ANTIGEN; CYCLOSPORIN A; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; T LYMPHOCYTE RECEPTOR; WORTMANNIN;

ANTIGEN EXPRESSION; ARTICLE; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; HUMAN; HUMAN CELL; LYMPHOCYTE CLONE; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL;

CALCIUM; CELL CYCLE; CYTOKINES; ENZYME INHIBITORS; FLOW CYTOMETRY; HUMANS; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN-2; TH1 CELLS; TH2 CELLS; UP-REGULATION;

EID: 0036097748     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000057750     Document Type: Article

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