The fate of the BlaI repressor during the induction of the Bacillus licheniformis BlaP β-lactamase

Molecular Microbiology

Volumn 44, Issue 3, 2002, Pages 685-694

  Filée, Patrice ^a   Benlafya, Kamal ^a   Delmarcelle, Michaël ^a   Moutzourelis, Georgios ^a   Frère, Jean Marie ^a   Brans, Alain ^a   Joris, Bernard ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

3,3' DITHIOBIS(SUCCINIMIDYL PROPIONATE); BACTERIAL PROTEIN; BETA LACTAMASE; PROTEIN BLAI; PROTEIN BLAP; PROTEIN BLAR1; PROTEIN BLAZ; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS LICHENIFORMIS; BACILLUS SUBTILIS; BACTERIAL CELL; BACTERIAL STRAIN; BINDING AFFINITY; CONTROLLED STUDY; CROSS LINKING; DNA BINDING; ENZYME SYNTHESIS; GENETIC VARIABILITY; ISOELECTRIC POINT; NONHUMAN; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN MODIFICATION; PROTEIN PURIFICATION; REPRESSOR GENE; SEQUENCE HOMOLOGY; TWO DIMENSIONAL GEL ELECTROPHORESIS;

BACILLUS; BACTERIAL PROTEINS; BETA-LACTAMASES; CARRIER PROTEINS; DIMERIZATION; DNA, BACTERIAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME INDUCTION; GENES, BACTERIAL; ISOELECTRIC FOCUSING; MODELS, GENETIC; PENICILLIN-BINDING PROTEINS; PENICILLINS; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS;

BACILLUS LICHENIFORMIS; BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); POSIBACTERIA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0036096597     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2002.02888.x     Document Type: Article

References (23)

1. The signal transducer (BlaRI) and the repressor (BlaI) of the Staphylococcus aureus beta-lactamase operon are inducible
2. β-lactamases of Staphylococcus aureus
3. Use of an ALFexpress DNA sequencer to analyze protein-nucleic acid interactions by band shift assay
4. Studies of the repressor (BlaI) of beta-lactamase synthesis in Staphylococcus aureus
5. Purification and DNA binding properties of the blaI gene product, repressor for the beta-lactamase gene, blaP, of Bacillus licheniformis
6. The penicillin sensory transducer, BlaR, involved in the inducibility of beta-lactamase synthesis in Bacillus licheniformis is embedded in the plasma membrane via a four-alpha-helix bundle
7. Expression in Escherichia coli of the carboxy terminal domain of the BLAR sensory-transducer protein of Bacillus licheniformis as a water-soluble Mr 26,000 penicillin-binding protein
8. Induction of β-lactamase and low-affinity penicillin binding protein 2′ synthesis in Gram-positive bacteria
9. A second regulatory gene, blaR1, encoding a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis
10. Proteolytic cleavage of the repressor (BlaI) of beta-lactamase synthesis in Staphylococcus aureus
11. ClpP of Bacillus subtilis is required for competence development, motility, degradative enzyme synthesis, growth at high temperature and sporulation
12. Repressor gene, blaI, for Bacillus licheniformis 749 beta-lactamase
13. Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system
14. The diversity, structure and regulation of beta-lactamases
15. Tn552, a novel transposable element from Staphylococcus aureus
16. Correlation between regulation of mecA transcription and expression of methicillin resistance in staphylococci
17. Differential transcription of the bla regulatory region during induction of beta-lactamase in Bacillus licheniformis
18. Analysis by transformation of the penicillinase system in Bacillus licheniformis
19. New shuttle vectors for Bacillus subtilis and Escherichia coli which allow rapid detection of inserted fragments
20. Regulation of the penicillinase genes of Bacillus licheniformis: Interaction of the pen repressor with its operators
21. Functional domains of the penicillinase repressor of Bacillus licheniformis
22. A proteolytic transmembrane signaling pathway and resistance to beta-lactams in staphylococci
23. Structure, function, and fate of the BlaR signal transducer involved in induction of beta-lactamase in Bacillus licheniformis