Desensitization of group I metabotropic glutamate receptors in rat sympathetic neurons

Journal of Neurophysiology

Volumn 87, Issue 4, 2002, Pages 1669-1676

  Kammermeier, Paul J ^a   Ikeda, Stephen R ^a  

^a GUTHRIE RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; ADENOSINE TRIPHOSPHATE; BISINDOLYLMALEIMIDE; CALCINEURIN INHIBITOR; CALCIUM ION; METABOTROPIC RECEPTOR; MYOSIN LIGHT CHAIN KINASE INHIBITOR; PHOSPHOTRANSFERASE; PROTEIN KINASE C INHIBITOR; STAUROSPORINE;

ANIMAL CELL; ARTICLE; CALCIUM BINDING; CHELATION; CONTROLLED STUDY; DESENSITIZATION; ENDOSOME; ENZYME INHIBITION; HYDROLYSIS; NERVE CELL; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; RAT; SYMPATHETIC NERVE CELL; SYNAPTIC TRANSMISSION;

EID: 0036095109     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00561.2001     Document Type: Article

References (38)

1. 2+ signal transduction
2. Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluR1, in transfected CHO cells
3. A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation
4. 2+ channels involves multiple receptor subtypes in cortical neurons
5. Functional regulation of metabotropic glutamate receptor type 1c: A role for phosphorylation in the desensitization of the receptor
6. Pharmacology and functions of metabotropic glutamate receptors
7. G-protein-coupled receptor kinase-mediated desensitization of metabotropic glutamate receptor 1a protects against cell death
8. Molecular determinants of metabotropic glutamate receptor signaling
9. Direct binding of G-protein βγ complex to voltage-dependent calcium channels
10. LHRH GTP-γ-S modify calcium current activation in bullfrog sympathetic neurons
11. Evolving concepts in G-protein-coupled receptor endocytosis: The role in receptor desensitization and signaling
12. 2+ pathway by phosphorylation of the receptor-G-protein coupling domain
13. Role of protein kinase C phosphorylation in rapid desensitization of metabotropic glutamate receptor 5
14. Glutamate metabotropic receptor inhibition of voltage-gated calcium currents in visceral sensory neurons
15. 2+ channels by G-protein βγ subunits
16. Functional switch from facilitation to inhibition in the control of glutamate release by metabotropic glutamate receptors
17. Voltage-dependent modulation of N-type calcium channels by G-protein βγ subunits
18. Heterologous expression of receptors and signaling proteins in adult mammalian sympathetic neurons by microinjection
19. Heterologous expression of metabotropic glutamate receptors in adult rat sympathetic neurons: Subtype-specific coupling to ion channels
20. Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: Comparison with mGluR1
21. 2+ channels
22. Rapid desensitization of group I metabotropic glutamate receptors is inhibited by high concentrations of staurosporine and bisindolymaleimide
23. q/11 and Gβγ
24. Molecular and catalytic properties of protein kinase C
25. Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö6976
26. Phosphorylation and calmodulin binding of the metabotropic glutamate receptor subtype 5 (mGluR5) are antagonistic in vitro
27. Protein kinase C inhibitors
28. Protein kinase C: History and perspectives
29. Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes
30. The metabotropic glutamate receptors: Their second intracellular loop plays a critical role in the G-protein coupling specificity
31. The structure and biological activities of the widely used protein kinase inhibitor, H7, differ depending on the commercial source
32. Switch from facilitation to inhibition of excitatory synaptic transmission by group I mGluR desensitization
33. Stimulus-dependent inhibition of platelet aggregation by the protein kinase C inhibitors polymyxin B, H-7, and staurosporine
34. Selective inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the rat hippocampus by activation of protein kinase C
35. 2-adrenoceptor
36. 2+ channels and synaptic transmission
37. Identification of PKC-isoform-specific biological actions using pharmacological approaches
38. When are class I metabotropic glutamate receptors necessary for long-term potentiation?