A new B-chain mutant of insulin: Comparison with the insulin crystal structure and role of sulfonate groups in the B-chain structure

Journal of Peptide Research

Volumn 60, Issue 1, 2002, Pages 56-64

  Dupradeau, F Y ^a   Le Flem, G ^a   Richard, T ^b   Monti, J P ^b   Oulyadi, H ^c   Prigent, Y ^c  

^a UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c UNIVERSITÉ DE ROUEN   (France)

Author keywords

Circular dichroism; H NMR; Insulin B chain; Molecular modeling; Sulfonate group

Indexed keywords

BOVINE INSULIN; INSULIN DERIVATIVE; MUTANT PROTEIN; SULFONIC ACID DERIVATIVE; TRIFLUOROETHANOL;

ARTICLE; BETA CHAIN; CIRCULAR DICHROISM; CONTROLLED STUDY; CRYSTAL STRUCTURE; HORMONE DETERMINATION; HORMONE STRUCTURE; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; CIRCULAR DICHROISM; INSULIN; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SULFONIC ACIDS;

BOVINAE;

EID: 0036094571     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2002.02990.x     Document Type: Article

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