Mice lacking α2-macroglobulin show an increased host defense against Gram-negative bacterial sepsis, but are more susceptible to endotoxic shock

European Cytokine Network

Volumn 13, Issue 1, 2002, Pages 86-91

  Hochepied, Tino ^a   Van Leuven, Fred ^a   Libert, Claude ^a  

^a Department of Molecular Biology ^*  (Belgium)

Author keywords

2 macroglobulin; Acute phase; Inflammation; Shock; TNF

Indexed keywords

ALPHA 2 MACROGLOBULIN; ENDOTOXIN;

ACUTE PHASE RESPONSE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; GRAM NEGATIVE INFECTION; HOST RESISTANCE; IMMUNITY; INFECTION SENSITIVITY; KNOCKOUT MOUSE; LETHALITY; MOUSE; NONHUMAN; PROTEIN FUNCTION; SEPSIS; SEPTIC SHOCK; SURVIVAL;

ANIMALS; BODY TEMPERATURE; COLONY COUNT, MICROBIAL; DISEASE SUSCEPTIBILITY; ENDOTOXINS; GENETIC PREDISPOSITION TO DISEASE; GRAM-NEGATIVE BACTERIAL INFECTIONS; IMMUNITY, NATURAL; INTERLEUKIN-6; KLEBSIELLA PNEUMONIAE; MACROGLOBULINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SEPSIS; SHOCK, SEPTIC; SURVIVAL RATE;

ANIMALIA; BACTERIA (MICROORGANISMS); MAMMALIA; NEGIBACTERIA;

EID: 0036093934     PISSN: 11485493     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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