Two more inv(16) acute myeloid leukemia cases with infrequent CBFβ-MYH11 fusion transcript: Clinical and molecular findings [4]

Haematologica

Volumn 87, Issue 5, 2002, Pages 554-555

  Martinelli, Giovanni ^a   Ottaviani, Emanuela ^a   Buonomici, Silvia ^a   Isidori, Alessandro ^a   Malagola, Michele ^a   Piccaluga, Pierpaolo ^a   Baccarani, Michele ^a  

^a Inst Hematol/Med Oncol Seragnoli   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CORE BINDING FACTOR; CORE BINDING FACTOR BETA; GENE PRODUCT; PROTEIN MYH11; UNCLASSIFIED DRUG; CBFBETA MYH11 FUSION PROTEIN; CBFBETA-MYH11 FUSION PROTEIN; DNA BINDING PROTEIN; MESSENGER RNA; ONCOPROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 2;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; CASE REPORT; EXON; FEMALE; GENE AMPLIFICATION; GENE FREQUENCY; GENE FUSION; GENE MUTATION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; LETTER; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; TREATMENT PLANNING; ACUTE DISEASE; CHROMOSOME 16; CHROMOSOME INVERSION; GENETICS; KARYOTYPING; MIDDLE AGED; MYELOID LEUKEMIA;

ACUTE DISEASE; ADULT; CHROMOSOMES, HUMAN, PAIR 16; DNA MUTATIONAL ANALYSIS; DNA-BINDING PROTEINS; FEMALE; HUMANS; INVERSION, CHROMOSOME; KARYOTYPING; LEUKEMIA, MYELOID; MIDDLE AGED; ONCOGENE PROTEINS, FUSION; RNA, MESSENGER; TRANSCRIPTION FACTOR AP-2; TRANSCRIPTION FACTORS;

EID: 0036090786     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (10)

1. Fusion between transcription factor CBFβ/PEBP2B and a myosin heavy chain in acute myeloid leukemia
2. Molecular analysis of granulocytic sarcoma: A single center experience
3. Molecular remission in PCR-positive acute myeloid leukemia patients with inv(16): Role of bone marrow transplantation procedures
4. Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia
5. Identification of a novel CBFβ-MYH11 fusion transcript in a patient with AML and inversion of chromosome 16
6. Prognosis value of residual disease monitoring by polymerase chain reaction in patients with CBFβ/MYH11-positive acute myeloblastic leukemia
7. Defining the "absence" of the CBFβ/MYH11 fusion transcript in patients with acute myeloid leukemia and inversion of chromosom 16 to predict long-term complete remission: A call for definitions
8. Detection of CBFβ/MYH11 fusion transcript in patients with inv (16), acute myeloid leukemia after allo geneic bone marrow or peripheral blood progenitor ce transplantation
9. Real-time quantitation of minimal resid ual disease in inv(16)-positive acute myeloid leukemia ma indicate risk for clinical relapse and may identify patient in a curable state
10. Long-term disease-free acute myeloblasti leukemia with inv(16) is associated with PCR undetectabl CBFβ/MYH11 transcript