Nω-nitro-L-arginine inhibits inducible HSP-70 via Ca2+, PKC, and PKA in human intestinal epithelial T84 cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 282, Issue 3 45-3, 2002, Pages

  Kiang, Juliann G ^a,b   Kiang, Sharon C ^a   Juang, Yuang Taung ^b   Tsokos, George C ^a,b  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Heat; Heat shock protein; Nitric oxide; Protein kinase A; Protein kinase C

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; FURA 2; HEAT SHOCK PROTEIN 70; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; N(G) NITROARGININE; PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR;

AEROBIC METABOLISM; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL NUCLEUS; CONCENTRATION RESPONSE; CYTOSOL; DOSE TIME EFFECT RELATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME PHOSPHORYLATION; HEAT STRESS; HUMAN; HUMAN CELL; IC 50; INHIBITION KINETICS; INTESTINE EPITHELIUM CELL; INTRACELLULAR TRANSPORT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN TRANSPORT;

EID: 0036087259     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00138.2001     Document Type: Article

References (54)

1. Endotoxin and steroid effects of nitric oxide synthase mRNA expression in rat lung and other tissues
2. Nω-nitro-L-arginine prolongs the survival time during the decompensatory phase of haemorrhagic shock in rats
3. Roles of nitric oxide in brain hypoxia-ischemia
4. Immunohistochemical detection of an estrogen-regulated protein by monoclonal antibodies
5. i
6. Heat shock factor-1 protein in heat shock factor-1 gene-transfected human epidermoid A431 cells requires phosphorylation before inducing heat shock protein-70 production
7. Overexpression of HSP-70 inhibits the phosphorylation of HSF1 by activating protein phosphatase and inhibiting protein kinase C activity
8. Expressional control of the constitutive isoforms of nitric oxide synthase (NOSI and NOSIII)
9. HSP-70 prevents activation of stress kinases
10. Thermotolerance, thermoresistance, and thermosensitization
11. HSP induction inhibits iNOS mRNA expression and attenuated hypotension in endotoxin-challenged rats
12. Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock
13. Heat shock proteins and macrophage resistance to the toxic effects of nitric oxide
14. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
15. Heat shock proteins as antigens in immunity against infection and self
16. Physiologic and molecular characterization of the role of nitric oxide in hemorrhagic shock: Evidence that type II nitric oxide synthase does not regulate vascular decompensation
17. Physiological and pharmacological inhibitors of luteinizing hormone-dependent steroidogenesis induce heat shock protein-70 in rat luteal cells
18. i or cAMP
19. i and protects human epidermoid A-431 cells after chemical hypoxia
20. i and protein kinases
21. Biochemical requirements for the expression of heat shock protein 72 kDa in human breast cancer MCF-7 cells
22. Regulation of heat shock protein 72 kDa and 90 kDa in human breast cancer MDA-MB-231 cells
23. Cell signaling and heat shock protein expression
24. Heat shock protein 70 kDa: Molecular biology, biochemistry, and physiology
25. Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-induced apoptosis by inducing heat shock protein 70 expression
26. Formation of nitric oxide from L-arginine in the central nervous system: A transduction mechanism for stimulation of the soluble guanylate cyclase
27. Nitric oxide synthesis in the CNS endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues
28. Nonspecific defense mechanism. The role of nitric oxide
29. Overexpression of the heat shock protein 70 enhances the TCR/CD3-and Fas/Apo-1/CD95-mediated apoptotic cell death in Jurkat cells
30. Time course and cellular localization of lipopolysaccharide-induced inducible nitric oxide synthase messenger RNA expression in the rat in vivo
31. Nitric oxide facilitates long-term potentiation, but not long-term depression
32. Nitric oxide donor induces HSP70 accumulation in the heart and in cultured cells
33. Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression
34. Nitric oxide: Physiology, pathophysiology, and pharmacology
35. In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation
36. 2+ is essential for multistep activation of the heat shock factor in permeabilized cells
37. Modulation of adriamycin transport by hyperthermia as measured by fluorescence-activated cell sorting
38. Coinduction of glucose-regulated proteins and doxorubicin resistance in Chinese hamster cells
39. Characterization of distinct heat shock- and thapsigargin-induced cytoprotective proteins in FRTL-5 thyroid cells
40. Heat shock protein 72 kD induction protects rat intestinal mucosa from ischemia/reperfusion injury
41. Invited opinion: Role of nitric oxide in hemorrhagic, traumatic, and anaphylactic shock and thermal injury
42. Nitric oxide mediates acute lung injury by modulation of inflammation
43. Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide
44. Adriamycin resistance, heat resistance and radiation response in Chinese hamster fibroblasts
45. A Sp 1 binding site of the tumor necrosis factor alpha promoter functions as a nitric oxide response element
46. Sustained nitric oxide production via L-arginine administration ameliorates effects of intestinal ischemia-reperfusion
47. Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia
48. Expression of iNOS in cultured rat epithelial pulmonary artery smooth muscle cells is inhibited by the heat shock response
49. The heat shock response inhibits inducible nitric oxide synthase gene expression by blocking I-κB degradation and NF-κB nuclear translocation
50. Nitric oxide induces heat-shock protein 70 expression in vascular smooth muscle cells via activation of heat shock 1
51. 2+ and protein kinase in the induction of the hsp70 gene
52. Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts
53. A synthetic peptide substrate for selective assay of protein kinase C
54. Evidence for a role of nitric oxide in hypovolemic hemorrhagic shock