Distinct patterns of downstream target activation are specified by the helix-loop-helix domain of proneural basic helix-loop-helix transcription factors

Developmental Biology

Volumn 247, Issue 1, 2002, Pages 137-148

  Talikka, Marja ^a   Perez, Sharon E ^b   Zimmerman, Kathryn ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Basic helix loop helix; Neurogenesis; Xash1; Xenopus; XNgnr1

Indexed keywords

HELIX LOOP HELIX PROTEIN; PROTEIN PRECURSOR; TRANSCRIPTION FACTOR; TUBULIN;

ARTICLE; CONTROLLED STUDY; FUSION GENE; GENE ACTIVATION; GENE CONSTRUCT; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE INDUCTION; GENE OVEREXPRESSION; GENE STRUCTURE; MULTIGENE FAMILY; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INDUCTION; STRUCTURE ACTIVITY RELATION; XENOPUS;

ANIMALIA; XENOPUS;

EID: 0036086770     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2002.0677     Document Type: Article

References (62)

1. Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins
2. A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and OTX homeodomain proteins
3. Regulation of neurogenesis by interactions between HEN1 and neuronal LMO proteins
4. The rhombotin family of cysteine-rich LIM-domain oncogenes: Distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13
5. The structure and expression of the Xenopus Krox-20 gene: Conserved and divergent pattern of expression in rhombomeres and neural crest
6. Misexpression of basic helix-loop-helix genes in the murine cerebral cortex affects cell fate choices and neuronal survival
7. Neuronal type information encoded in the basic-helix-loop-helix domain of proneural genes
8. Sensitivity of proneural genes to lateral inhibition affects the pattern of primary neurons in the Xenopus embryo
9. The MyoD DNA binding domain contains a recognition code for muscle- specific gene activation
10. Acquisition of myogenic specificity by replacement of three amino acid residues from MyoD into E12
11. Acquisition of myogenic specificity through replacement of one amino acid of MASH-1 and introduction of an additional alpha helical turn
12. XCoe2, a transcription factor of the Col/Olf-1/EBF family involved in the specification of primary neurons in Xenopus
13. Generation of neurons by transient expression of neural bHLH proteins in mammalian cells
14. XASH genes promote neurogenesis in Xenopus embryos
15. XASH1, a Xenopus homolog of achaete-scute: A proneural gene in anterior regions of the vertebrate CNS
16. A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons
17. The homeodomain-containing gene Xdbx inhibits neuronal differentiation in the developing embryo
18. Sequence and expression patterns of two forms of the middle molecular weight neurofilament protein (NF-M) of Xenopus laevis
19. Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons
20. In situ hybridization: An improved whole mount method for Xenopus embryos
21. Cephalic expression and molecular characterization of Xenopus En-2
22. Localization of specific mRNAs in Xenopus embryos by whole-mount in situ hybridization
23. Inhibition of activin receptor signaling promotes neuralization in Xenopus
24. Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa2 motif
25. Expression of LMO-4 in the central nervous system of the embryonic and adult mouse
26. Primary structure and expression of a functional human glucocorticoid receptor cDNA
27. HEB, a basic helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors
28. Atonal is a proneural gene that directs chordotonal formation in the Drosophila peripheral nervous system
29. The specificity of proneural genes in determining Drosophila sense organ identity
30. Periodic repression of Notch pathway genes governs the segmentation of Xenopus embryos
31. DNA binding and transcriptional regulatory activity of mammalian achaete-scute homologous (MASH) proteins revealed by interaction with a muscle-specific enhancer
32. Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis
33. Xath1, a vertebrate homolog of Drosophila atonal, induces neuronal differentiation within ectodermal progenitors
34. MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer
35. Functional activity of myogenic HLH proteins requires heterooligomerization with E12/E47-like proteins in vivo
36. Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein
37. Basic helix-loop-helix genes in neural development
38. MASH1 activates expression of the paired homeodomain transcription factor Phox2a, and couples pan-neuronal and subtype-specific components of autonomic neuronal identity
39. Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells
40. Crystal structure of MyoD bHLH domain-DNA complex: Perspectives on DNA recognition and implications for transcriptional activation
41. Identification of neurogenin, a vertebrate neuronal determination gene
42. Primitive erythropoiesis in the Xenopus embryo: The synergistic role of LMO-2, SCL and GATA-binding proteins
43. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins
44. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence
45. ME1 and GE1: Basic helix-loop-helix transcription factors expressed at high levels in the developing nervous system and in morphogenetically active regions
46. Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity
47. Early specification of sensory neuron fate revealed by expression and function of neurogenins in the chick embryo
48. X-ngnr-1 and Xath3 promote ectopic expression of sensory neuron markers in the neurula ectoderm and have distinct inducing properties in the retina
49. Interactions between chip and the achaete/scute-daughterless heterodimers are required for pannier-driven proneural patterning
50. Gene expression in the embryonic nervous system of Xenopus laevis
51. TTG-2, a new gene encoding a cysteine-rich protein with the LIM motif, is overexpressed in acute T-cell leukaemia with the t(11;14)(p13; q11)
52. Xenopus embryos regulate the nuclear localization of XMyoD
53. Embryonic expression and evolution of duplicated E-protein genes in Xenopus laevis: Parallels with ancestral E-protein genes
54. Identification of non-tissue-specific helix-loop-helix genes in Xenopus laevis
55. Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction
56. Conversion of ectoderm into a neural fate by ATH-3 a vertebrate basic helix-loop-helix gene homologous to Drosophila proneural gene atonal
57. MyoD1: A nuclear phosphoprotein requiring a myc homology region to convert fibroblasts to myoblasts
58. Expression of LIM-domain binding protein (ldb) genes during zebrafish embryogenesis
59. Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate
60. Expression of the basic helix-loop-helix ME1 E-protein during development and aging of the murine cerebellum
61. Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia
62. The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes