Infrequent p53 gene mutations and lack of p53 protein expression in clear cell sarcoma of the kidney: Immunohistochemical study and mutation analysis of p53 in renal tumors of unfavorable prognosis

Modern Pathology

Volumn 15, Issue 6, 2002, Pages 606-610

  Hsueh, Chuen ^a   Wang, Hao ^c   Gonzalez Crussi, Frank ^c   Lin, Jer Nan ^b   Hung, Iou Jih ^b   Yang, Chao Ping ^b   Jiang, Tang Her ^b  

^a Chang Gung Children Hospital   (Taiwan)

^b CHANG GUNG CHILDREN S HOSPITAL   (Taiwan)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Anaplastic; Clear cell sarcoma of the kidney; Malignant rhabdoid tumor of the kidney; P53; Wilms' tumor

Indexed keywords

PROTEIN P53;

ADULT; ANAPLASTIC CARCINOMA; ARTICLE; CLEAR CELL SARCOMA; CLINICAL ARTICLE; FEMALE; GENE MUTATION; GENETIC ANALYSIS; HUMAN; IMMUNOHISTOCHEMISTRY; INFANT; KIDNEY SARCOMA; KIDNEY TUMOR; MALE; NEPHROBLASTOMA; NEWBORN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RHABDOID TUMOR; SINGLE STRAND CONFORMATION POLYMORPHISM;

ADOLESCENT; AGED; BASE SEQUENCE; CHILD; CHILD, PRESCHOOL; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; INFANT, NEWBORN; KIDNEY NEOPLASMS; MALE; MUTAGENESIS, INSERTIONAL; MUTATION; POINT MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROGNOSIS; RHABDOID TUMOR; SARCOMA, CLEAR CELL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0036085678     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3880573     Document Type: Article

References (26)

1. Clear cell sarcoma of the kidney. A clinicopathological study of 21 patients with long-term follow-up evaluation
2. Clear cell sarcoma of the kidney: A review of 351 cases from the National Wilms Tumor Study Group Pathology Center
3. Rhabdoid tumor of kidney. A report of 111 cases from the National Wilms' Tumor Study Pathology Center
4. P53 mutations in human cancers
5. Immunohistochemical detection of p53 protein in rhabdomyosarcoma: Association with clinicopathological features and outcome
6. The relationship between p53 mutations and overexpression of p53 and prognosis in malignant gliomas of childhood
7. Immunohistochemical detection of p53 in Wilms' tumors correlates with unfavorable outcome
8. P53 protein expression in nephroblastomas: A predictor of poor prognosis
9. Aberrant expression of the tumour suppressor gene p53 is very frequent in Wilms' tumours
10. Immunophenotype, mRNA expression, and gene structure of p53 in Wilms' tumors
11. Mutations of p53 in Wilms' tumors
12. Anaplastic Wilms' tumour, a subtype displaying poor prognosis, harbours p53 gene mutations
13. Mutations of the p53 tumor suppressor gene occur infrequently in Wilms' tumor
14. Infrequency of ras, p53, WT1, or RB gene alterations in Wilms' tumors
15. Implications of p53 protein expression in clear cell sarcoma of the kidney
16. Intracranial metastasis from clear cell sarcoma of the kidney: A case report
17. Comparative genomic hybridization analysis of clear cell sarcoma of the kidney
18. Genetic analysis of clear cell sarcoma (CCSK) by comparative genomic hybridization (CGH)
19. The polymerase chain reaction and the molecular genetic analysis of tissue biopsies
20. P53 tumour-suppressor gene mutations are mainly localized on exon 7 in human primary and metastatic prostate cancer
21. Translocation 10;17 in clear cell sarcoma of the kidney. A first report
22. Malignant rhabdoid tumor of the colon: Report of a case with molecular analysis
23. Immunohistochemical and cytogenetic findings in malignant rhabdoid tumor
24. Establishment and characterization of two cultured cell lines derived from malignant rhabdoid tumors of the kidney
25. Establishment and molecular characterization of five cell lines derived from renal and extrarenal malignant rhabdoid tumors