Melatonin phase shifts human circadian rhythms in a placebo-controlled simulated night-work study

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 282, Issue 2 51-2, 2002, Pages

  Sharkey, Katherine M ^a   Eastman, Charmane I ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Body temperature; Constant routine; Humans; Jet lag; Shift work; Sleep; Sleepiness; Workschedule tolerance

Indexed keywords

MELATONIN; PLACEBO;

ADAPTATION; ADULT; ARTICLE; BODY TEMPERATURE; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HORMONE ACTION; HUMAN; JET LAG; MALE; NIGHT; PRIORITY JOURNAL; SIMULATION; SLEEP; TRAVEL; WORK SCHEDULE;

EID: 0036081522     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00135.2001     Document Type: Article

References (57)

1. Alleviation of jet lag by melatonin: Preliminary results of controlled double blind trial
2. Melatonin phase advances circadian rhythm
3. Bright light effects on body temperature, alertness, EEG and behavior
4. Intermittent bright light and exercise to entrain human circadian rhythms to night work
5. The sleep-evoked decrease of body temperature
6. Melatonin and light induce phase shifts of circadian activity rhythms in the C3H/HeN mouse
7. Bright light, dark and melatonin can promote circadian adaptation in night shift workers
8. Melatonin: A major regulator of the circadian rhythm of core temperature in humans
9. Estimating the endogenous circadian temperature rhythm without keeping people awake
10. Dose-dependent entrainment of rat circadian rhythms by daily injection of melatonin
11. Melatonin and jet lag: Confirmatory result using a simplified protocol
12. Bright light resets the human circadian pacemaker independent of the timing of the sleep-wake cycle
13. Delayed sleep phase syndrome response to melatonin
14. Timed exposure to bright light improves sleep and alertness during simulated night shifts
15. Melatonin and sleep in humans
16. Improving adaptation to simulated night shift: Timed exposure to bright light versus daytime melatonin administration
17. Melatonin-induced temperature suppression and its acute phase-shifting effects correlate in a dose-dependent manner in humans
18. Acute phase-shifting effects of melatonin associated with suppression of core body temperature in humans
19. How to use light and dark to produce circadian adaptation to night shift work
20. Evening alcohol consumption alters the circadian rhythm of body temperature
21. The pragmatic approach to masking
22. Can melatonin improve shift workers' tolerance of the night shift? Some preliminary findings
23. Melatonin suppression by light depends on light history
24. Effect of light history on light sensitivity in humans
25. Quantification of sleepiness: A new approach
26. Self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms
27. Can melatonin improve adaptation to night shift?
28. Does exogenous melatonin improve day sleep or night alertness in emergency physicians working night shifts?
29. Effect of sex, menstrual cycle phase and oral contraceptive use on circadian temperature rhythms
30. Early evening melatonin and S-20098 advance circadian phase and nocturnal regulation of core body temperature
31. Melatonin shifts human circadian rhythms according to a phase-response curve
32. The human phase response curve (PRC) to melatonin is about 12 hours out of phase with the PRC to light
33. Melatonin administration can entrain the free-running circadian system of blind subjects
34. Effects of a four-day nocturnal melatonin treatment on the 24 h plasma melatonin, cortisol and prolactin profiles in humans
35. Medium-intensity light produces circadian rhythm adaptation to simulated night-shift work
36. Melatonin directly resets the rat suprachiasnmatic circadian clock in vitro
37. Adaptation to abrupt time shifts of the oscillator(s) controlling human circadian rhythms
38. Nonsteroidal anti-inflammatory drugs alter body temperature and suppress melatonin in humans
39. Delayed sleep phase syndrome: A placebo-controlled cross-over study on the effects of melatonin administered five hours before the individual dim light melatonin onset
40. Melatonin and delayed sleep phase syndrome: Ambulatory polygraphic evaluation
41. A double-blind trial of melatonin as a treatment for jet lag in international cabin crew
42. Free-running activity rhythms in the rat: Entrainment by melatonin
43. Melatonin administration promotes circadian adaptation to night-shift work
44. Melatonin administration to night-shift workers: An update
45. Entrainment of free-running circadian rhythms by melatonin in blind people
46. Melatonin as a chronobiotic: Treatment of circadian desynchrony in night workers and the blind
47. Activity-based sleep-wake identification: An empirical test of methodological issues
48. Influence of melatonin treatment on human circadian rhythmicity before and after a simulated 9-hr time shift
49. Effects of melatonin administration on daytime sleep after simulated night shift work
50. Locomotor activity rhythm in the field mouse Mus booduga phase-shifts to melatonin injections in a dose-dependent manner
51. Jet lag: Clinical features, validation of a new syndrome-specific scale, and lack of response to melatonin in a randomized, double-blind trial
52. Comparative study to determine the optimal melatonin dosage form for the alleviation of jet lag
53. Melatonin instantaneously resets intrinsic circadian rhythmicity in the rat suprachiasmatic nucleus
54. The effects of melatonin on the timing of sleep in patients with delayed sleep phase syndrome
55. Melatonin is able to influence its secretion in humans: Description of a phase-response curve