Jet lag: Clinical features, validation of a new syndrome-specific scale, and lack of response to melatonin in a randomized, double-blind trial

American Journal of Psychiatry

Volumn 156, Issue 9, 1999, Pages 1392-1396

  Spitzer, Robert L ^a   Terman, Michael ^b   Williams, Janet B W ^b   Terman, Jiuan Su ^b   Malt, Ulrik F ^b   Singer, Forbes ^b   Lewy, Alfred J ^b  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MELATONIN;

ADULT; AGED; ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; JET LAG; MAJOR CLINICAL STUDY; MALE; NORWAY; OUTCOMES RESEARCH; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SCORING SYSTEM; TREATMENT OUTCOME;

AEROSPACE MEDICINE; CIRCADIAN RHYTHM; DOUBLE-BLIND METHOD; HEALTH STATUS; HUMANS; MELATONIN; PLACEBOS; QUESTIONNAIRES; SEVERITY OF ILLNESS INDEX; SLEEP DEPRIVATION; SLEEP DISORDERS; TRAVEL; TREATMENT OUTCOME;

EID: 0032860720     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Winget CM, DeRoshia CW, Markley CL, Holley DC: A review of human physiological and performance changes associated with desynchronosis of biological rhythms. Aviat Space Environ Med 1984; 55:1085-1096
2. Comperatore CA, Krueger GP: Circadian rhythm desynchronosis, jet lag, shift lag, and coping strategies. Occup Med 1990; 5:323-341
3. Klein KE, Wegmann HM, Athanassenas G, Hohlweck H, Kuklinski P: Air operations and circadian performance rhythms. Aviat Space Environ Med 1976; 17:221-230
4. Graeber RC: Alterations in performance following rapid transmeridian flight, in Rhythmic Aspects of Behavior. Edited by Brown FM, Graeber RC. Hillsdale, NJ, Lawrence Erlbaum Associates, 1982, pp 173-212
5. Aschoff J, Hoffmann K, Pohl H, Wever R: Re-entrainment of circadian rhythms after phase-shifts of the Zeitgeber. Chronobiologia 1975; 2:23-78
6. Klein KE, Wegmann HM: Significance of circadian rhythms in aerospace operations, in NATO: AGARDograph 247. Edited by the Advisory Group for Aerospace Research and Development. London, NATO Technical Editing and Reproduction, 1980, pp 1-60
7. Brody JE: Debate aside, melatonin can reset the body's clock. New York Times, Sept 27, 1995, p C9
8. Lewy AJ, Ahmed S, Jackson JM, Sack RL: Melatonin shifts human circadian rhythms according to a phase-response curve. Chronobiol Int 1992; 9:380-392
9. Wirz-Justice A, Armstrong SM: Melatonin: nature's soporific? J Sleep Res 1996; 5:137-141
10. Zhdanova IV, Wurtman RJ: Efficacy of melatonin as a sleep-promoting agent. J Biol Rhythms 1997; 12:644-650
11. Arendt J, Aldhous ME, Marks V: Alleviation of jet lag by melatonin: preliminary results of controlled double blind trial. BMJ 1986; 292:1170
12. Arendt J, Aldhous ME, English J, Marks V, Ardent JH: Some effects of jet lag and their alleviation by melatonin. Ergonomics 1987; 30:1379-1393
13. Skene DJ, Aldhous ME, Ardent J: Melatonin, jet-lag and sleep-wake cycle, in Sleep '88. Edited by Horn J. New York, Gustav Fisher Verlag, 1989, pp 39-41
14. Petrie K, Conaglen JV, Thompson L, Chamberlain K: Effect of melatonin on jet lag after long haul flights. BMJ 1989; 298: 705-707
15. Nickelsen T, Lang A, Bergau L: The effect of 6-, 9- and 11-hour time shifts on circadian rhythms: adaptation of sleep parameters and hormonal patterns following the intake of melatonin or placebo. Advances in Pineal Res 1991; 5:303-309
16. Claustrat B, Brun J, David M, Sassolas G, Chazot G: Melatonin and jet lag: confirmatory results using a simplified protocol. Biol Psychiatry 1992; 32:705-711
17. Petrie K, Dawson AG, Thompson L, Brook R: A double-blind trial of melatonin as a treatment for jet lag in international cabin crew. Biol Psychiatry 1993; 33:526-530
18. Suhner A, Schlagenhauf P, Johnson R, Tschopp A, Steffen R: Comparative study to determine the optional melatonin dosage form for the alleviation of jet lag. Chronobiol Int 1998; 15: 655-666
19. Arendt J, Skene DJ, Middleton B, Lockley SW, Deacon S: Efficacy of melatonin treatment in jet lag, shift work and blindness. J Biol Rhythms 1997; 12:604-617
20. Samel A, Wegmann HM, Vejvoda M, Maass H, Gundel A, Schutz M: Influence of melatonin treatment on human circadian rhythmicity before and after a simulated 9-hr time shift. J Biol Rhythms 1991; 6:235-248
21. Deacon S, Arendt J: Adapting to phase shifts, II: effects of melatonin and conflicting light treatment. Physiol Behav 1996; 59:675-682
22. Lewy AJ, Bauer AK, Ahmed S, Thomas KJ, Cutler NL, Singer NM, Moffit MT, Sack RL: The human phase response curve (PRC) to melatonin is about 12 hours out of phase with the PRC to light. Chronobiol Int 1998; 15:71-83
23. Boulos Z, Campbell SS, Lewy AJ, Terman M, Dikj D-J, Eastman CI: Light treatment for sleep disorders: consensus report, VII: jet lag. J Biol Rhythms 1995; 10:167-176
24. Lewy AJ, Bauer VK, Cutler NL, Sack RL: Melatonin treatment of winter depression: a pilot study. Psychiatry Res 1998; 77: 57-61