Effect of thalidomide in different tumors in rodents

Journal of Experimental Therapeutics and Oncology

Volumn 2, Issue 3, 2002, Pages 158-162

  Palencia, Guadalupe ^a   Arrieta, Oscar ^a   Ríos, Camilo ^b   Altagracia, Marina ^c   Kravzov, Jaime ^c   Sotelo, Julio ^a  

^a The Laboratories of Neuroimmmunology   (Mexico)

^b NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^c UNIVERSIDAD AUTÓNOMA METROPOLITANA   (Mexico)

Author keywords

Angiogenesis; Ethyl nitrosourea; Glioblastoma; Melanoma; Thalidomide

Indexed keywords

THALIDOMIDE; ANGIOGENESIS INHIBITOR;

ANGIOGENESIS; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; EXPERIMENTAL NEOPLASM; GLIOBLASTOMA; GROWTH INHIBITION; MITOSIS; NERVOUS SYSTEM TUMOR; NONHUMAN; PRIORITY JOURNAL; RAT; TUMOR GROWTH; ANIMAL; BRAIN TUMOR; CANCER TRANSPLANTATION; EXPERIMENTAL MELANOMA; WISTAR RAT;

ANGIOGENESIS INHIBITORS; ANIMAL; BRAIN NEOPLASMS; GLIOBLASTOMA; MELANOMA, EXPERIMENTAL; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; RATS; RATS, WISTAR; SUPPORT, NON-U.S. GOV'T; THALIDOMIDE; ANIMALS;

EID: 0036081073     PISSN: 13594117     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1359-4117.2002.01011.x     Document Type: Article

References (22)

1. Thalidomide in the treatment of cancer
2. A combination of talidomide plus antibiotics protecs rabbits from mycobacterial meningitis-associated death
3. Inhibitory effects of thalidomide on cellular proliferation, endoneurial edema and myelin phagocytosis during early wallerian degeneration
4. Thalidomide promotes metastasis of prostate adenocarcinoma cells (PA-III) in L-W rats
5. Thalidomide costimulates primary human T limphocytes, preferentially inducing proliferation, citokine production and cytotoxic responses in the CD8+ subset
6. Thalidomide and a thalidomide analogue inhibit endotelial cell proliferation in vitro
7. Frequent good partial remissions from thalidomide including best response ever in patients with advanced refractory and relapsed myeloma
8. Animal models in drug development
9. Evidence for teratogenicity of thalidomide using congenic and recombinant inbred rat strains
10. Novel biological response modifiers: Phthalimides with TNF-alpha production regulating activity
11. Thalidomide is an inhibitor of angiogenesis
12. Angiogenesis research enjoys growth spurt in the 1990s
13. Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization
14. The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen- and antigen-stimulated human peripheral blood mononuclear cell cultures
15. Mechanism of action in thalidomide teratogenesis
16. Interaction of Thalidomide with DNA of rabbit embryos: A possible explication for its immunosuppressant and teratogenic effects
17. Is thalidomide mutagenic?
18. Thalidomide and its metabolites have no effect on human lymphocyte proliferation
19. Thalidomide may not be a mutagen
20. Induction of morphological differentiation in the human leukemic cell line K 562 by exposure to thalidomide metabolites
21. Teratogen metabolism: Activation of thalidomide and thalidomide analogues to products that inhibit the attachment of cells to concanavalin A coated plastic surfaces
22. Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity