Expression and localization of inhibin α, inhibin/activin βA and βB and the activin type II and inhibin β-glycan receptors in the developing human testis

Reproduction

Volumn 123, Issue 6, 2002, Pages 779-788

  Anderson, R A ^a   Cambray, N ^a   Hartley, P S ^a   McNeilly, A S ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; ACTIVIN BETAA; ACTIVIN BETAB; ACTIVIN RECEPTOR; ACTIVIN RECEPTOR 2; ACTIVIN RECEPTOR TYPE 2A; ACTIVIN RECEPTOR TYPE 2B; CYTOKINE RECEPTOR; GLYCAN DERIVATIVE; INHIBIN; INHIBIN ALPHA; INHIBIN BETAA; INHIBIN BETAB; INHIBIN RECEPTOR; MESSENGER RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; EPIDIDYMIS; FETUS; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEYDIG CELL; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; RETE TESTIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEMINIFEROUS TUBULE; SERTOLI CELL; TESTIS CELL;

EID: 0036079581     PISSN: 14701626     EISSN: None     Source Type: Journal    
DOI: 10.1530/rep.0.1230779     Document Type: Article

References (57)

1. Serum inhibin B levels reflect Sertoli cell function in normal men and men with testicular dysfunction
2. Physiological relationships between inhibin B, FSH and spermatogenesis in normal men and response to gonadotrophin suppression by exogenous testosterone
3. Different roles of prepubertal and postpubertal germ cells and Sertoli cells in the regulation of serum inhibin B levels
4. Fibroblast growth factor 3, a protein with dual subcellular localization, is targeted to the nucleus and nucleolus by the concerted action of two nuclear localization signals and a nucleolar retention signal
5. Identification of a nuclear localization signal in activin/inhibin betaA subunit; intranuclear betaA in rat spermatogenic cells
6. Activin stimulates Sertoli cell proliferation in a defined period of rat testis development
7. Insertion of Inhbb into the Inhba locus rescues the Inhba-null phenotype and reveals new activin functions
8. Inhibin: Definition and nomenclature, including related substances
9. Embryology of mammalian gonads and ducts
10. Inhibin and activin as paracrine/autocrine factors
11. Structure and expression of a membrane component of the inhibin receptor system
12. Activin receptor mRNA expression in rat testicular cell types
13. Peritubular myoid cells from immature rat testes secrete activin-A and express activin receptor type II in vitro
14. Developmental and cyclic adenosine 3′,5′ monophosphate-dependent regulation of inhibin subunit messenger ribonucleic acids in human fetal testes
15. Roles of activin and its signal transduction mechanisms in reproductive tissues
16. Differential control of gonadotrophin secretion in the human: Endocrine role of inhibin
17. The genetic control and germ cell kinetics of the female and male germ line in mammals including man
18. Heterodimers and homodimers of inhibin subunits have different paracrine actions in the modulation of luteinizing hormone-stimulated androgen biosynthesis
19. Inhibin-B: A likely candidate for the physiologically important form of inhibin in men
20. Differential localization of inhibin subunit proteins in the ovine testis during fetal gonadal development
21. TGF-beta family members and gonadal development
22. Expression of inhibin βA and βB, follistatin and activin-A receptor messenger ribonucleic acids in the rat seminiferous epithelium
23. Sex differences in the action of activin-A on cell proliferation of differentiating rat gonad
24. Nucleolar association of fibroblast growth factor 3 via specific sequence motifs has inhibitory effects on cell growth
25. Differential patterns of inhibin secretion in response to gonadotrophin stimulation in normal men
26. Localization of inhibin and activin binding sites in the testis during development by in situ ligand binding
27. Male reproductive phenotypes in double mutant mice lacking both FSHbeta and activin receptor IIA
28. Betaglycan binds inhibin and can mediate functional antagonism of activin signalling
29. Regulation of Leydig cell function in primary culture by activin and inhibin
30. Rams produce inhibin A not B: Changes in plasma inhibin A during testis growth and expression of inhibin/activin subunit mRNA and protein in the testis
31. Testicular expression of inhibin and activin subunits and follistatin in the rat and human fetus and neonate and during postnatal development in the rat
32. TGF-beta signal transduction
33. Activin stimulates spermatogonial proliferation in germ-Sertoli cell co-cultures from immature rat testis
34. Activins, inhibins, and follistatins: Further thoughts on a growing family of regulators
35. In search of binding-identification of inhibin receptors
36. Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice
37. Functional analysis of activins during mammalian development
38. Different phenotypes for mice deficient in either activins or activin receptor type II
39. Regulation of germ cell and Sertoli cell development by activin, follistatin and FSH
40. Human fetal testis: Second trimester proliferative and steroidogenic capacities
41. Genetic and cellular analysis of male germ cell development
42. The role of follicle-stimulating hormone in controlling Sertoli cell proliferation in testes of fetal rats
43. Localization and secretion of inhibin/activin subunits in the human and subhuman primate fetal gonads
44. Immuno- and bioactive inhibin and inhibin alpha-subunit expression in rat Leydig cell cultures
45. Is the action of inhibin mediated via a unique receptor?
46. Tissue-specific expression of inhibin/activin subunit and follistatin mRNAs in mid- to late-gestational age human fetal testis and epididymis
47. Expression of messenger ribonucleic acids encoding the inhibin/activin system during mid- and late-gestation rat embryogenesis
48. Germ cell specific expression of c-kit in the human fetal gonad
49. Spatiotemporal patterns of expression of neurotrophins and neurotrophin receptors in mice suggest functional roles in testicular and epididymal morphogenesis
50. Hormones and testis development and the possible adverse effects of environmental chemicals
51. Male sterility in transgenic mice expressing activin βA subunit gene in testis
52. Inhibin reduces spermatogonial numbers in testes of adult mice and Chinese hamsters
53. Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction
54. Differentiation of the fetal gonad
55. Dimeric inhibins in amniotic fluid, maternal serum and fetal serum in human pregnancy
56. Differentiation and development of the testes