Synthesis of nonluminescent lanthanide(III) chelates tethered to an aminooxy group and their applicability to biomolecule derivatization

Bioconjugate Chemistry

Volumn 13, Issue 4, 2002, Pages 876-880

  Peuralahti, Jari ^a   Puukka, Katri ^a   Hakala, Harri ^a   Mukkala, Veli Matti ^a   Mulari, Outi ^a   Hurskainen, Pertti ^a   Hovinen, Jari ^a  

^a Wallac Oy   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOMOLECULES; CHELATION; KETONES; PROTEINS;

AMINOOXY GROUPS; APPLICATION DATA; DERIVATIZATIONS; DIETHYLENETRIAMINETETRAACETIC ACID; N-TERMINALS; OLIGOPEPTIDES; PRE-OXIDATION; SERINE RESIDUES; SYNTHETIC DRUG;

RARE EARTH ELEMENTS;

AMIDE; AMINE; CARBOXYLIC ACID; CHELATING AGENT; CROSS LINKING REAGENT; HAPTEN; INTERLEUKIN 8; LANTHANIDE; PROTEIN;

ARTICLE; CHEMISTRY; FLUORESCENCE; HUMAN; PROTEIN BINDING;

AMIDES; AMINES; CARBOXYLIC ACIDS; CHELATING AGENTS; CROSS-LINKING REAGENTS; FLUORESCENCE; HAPTENS; HUMANS; INTERLEUKIN-8; LANTHANOID SERIES ELEMENTS; PROTEIN BINDING; PROTEINS;

EID: 0036074741     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc025502b     Document Type: Article

References (21)

1. Mechanism and catalysis of simple carbonyl group reactions
2. Selective 3-(O-carboxymethyl)oxime formation in steroidal 3,-20-diones for hapten immunospecificity
3. Introduction of aliphatic amino and hydroxy groups to keto steroids using O-substituted hydroxylamines
4. A novel, sensitive and specific assay of abasic sites, the most commonly produced DNA lesions
5. Synthesis of fluorescent probes for the detection of abasic sites in DNA
6. The oxyamino-aldehyde coupling reaction: An efficient method for the derivatization of oligonucleotides
7. Detection of abasic sites on individual DNA molecules using atomic force microscopy
8. Construction of protein analogues by site-specific condensation of unprotected fragments
9. A fluorescent interleukin-8 receptor probe produced by targetted labeling at the amino terminus
10. Site-directed conjugation of nonpeptide groups to peptides and proteins via periodite oxidation of a 2-amino alcohol. Application to modification at N-terminal serine
11. Chemoselective ligation reactions with proteins, oligosaccharides and cells
12. Molecular hybridization probes prepared with 4-aminooxybutylamine
13. Aminooxy functionalized oligonucleotides: Preparation, on-support derivatization and postsynthetic attachment to polymer support
14. Time-resolution in fluorometry technologies, labels, and applications in bioloanalytical assays
15. Applications of fluorescence in immunoassays
16. LANCE vs HTRF technologies (or vice versa)
17. LANCE: Homogeneous assay platform for HTS
18. HTRF technology
19. Rare earth cryptates and homogeneous fluoroimmunoassays with human sera
20. Introduction of lanthanide(III) chelates to oligopeptides on solid phase