The oxyamino-aldehyde coupling reaction: An efficient method for the derivatization of oligonucleotides

Tetrahedron Letters

Volumn 38, Issue 50, 1997, Pages 8687-8690

  Trévisiol, Emmanuelle ^a   Renard, Annabelle ^a   Defrancq, Eric ^a   Lhomme, Jean ^a  

^a UNIVERSITÉ JOSEPH FOURIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGODEOXYRIBONUCLEOTIDE; OLIGONUCLEOTIDE;

ARTICLE; DERIVATIZATION; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MASS SPECTROMETRY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0043040420     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)10335-5     Document Type: Article

References (11)

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7. 8 In the present case, the absence of oxidation could be attributed to decreased reactivity at sulfur due to electronic delocalisation on the purine ring.
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10. 2O. The probe temperature was 25°C and the spin rate was about 3600 Hz. The 1-D spectrum was obtained with 128 transients and a presaturation delay of 3s. The 2-D correlation map consisted of 512 × 1K data points spectra, each composed of 128 transients.
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