Manual solid phase synthesis of potent peptide analogs

Chinese Pharmaceutical Journal

Volumn 54, Issue 2, 2002, Pages 141-147

  Tsai, Jia Yin ^a   Lung, Feng Di T ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Phosphopeptide; Signal transduction; Solid phase peptide synthesis

Indexed keywords

CLONING; PROTEINS;

MANUAL SYNTHESIS;

ESCHERICHIA COLI;

GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; PHOSPHOPEPTIDE; SYNTHETIC PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; DRUG SYNTHESIS; ESCHERICHIA COLI; FREEZE DRYING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PEPTIDE SYNTHESIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; SOLID; SRC HOMOLOGY DOMAIN;

EID: 0036070525     PISSN: 10161015     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Nonphosphorylated peptide ligands for the Grb2 Src homology 2 domain
2. Characterization of p21Cip1/Waf1 peptide domains required for cyclin E/Cdk2 and PCNA interaction
3. Opiate aromatic pharmacophore structure-activity relationships in CTAP analogues determined by topographical bias, two-dimensional NMR, and biological activity assays
4. An approach to cyclic peptide libraries: Reducing epimerization in medium sized rings during solid phase peptide synthesis
5. Chemical synthesis of peptides and proteins
6. Functional preference of the constituent amino acid residues in a phage-library-based nonphosphorylated inhibitor of the Grb2-SH2 domin
7. Solution structure and dynamics of G1TE, a nonphosphorylated cyclic peptide inhibitor for the Grb2 SH2 domain
8. Preparation and application of the 5-(4-(9-Fluorenylmethyloxycarbonyl)-aminomethyl-3,5-dimethoxyphenoxy)-valeric acid (PAL) handle for the solid-phase synthesis of C-terminal peptide amides under mild conditions
9. Synthesis and characterization of defenson NP-1
10. Significant compensatory role of position Y-2 conferring high affinity to non-phosphorylated inhibitors of Grb2-SH2 domain