KCa channel blockers reveal hyperpolarization and relaxation to K+ in rat isolated mesenteric artery

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 283, Issue 2 52-2, 2002, Pages

  Dora, Kim A ^a   Ings, Nicola T ^a   Garland, Christopher J ^a  

^a University of Bath   (United Kingdom)

Author keywords

Contraction; Dilatation; Membrane potential; Na+ K+ ATPase; Smooth muscle

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); APAMIN; CHARYBDOTOXIN; IBERIOTOXIN; PHENYLEPHRINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION;

ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BLOOD VESSEL TONE; CALCIUM CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; ENZYME ACTIVATION; HYPERPOLARIZATION; MALE; MEMBRANE POTENTIAL; MESENTERIC ARTERY; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; POTASSIUM TRANSPORT; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE; VASODILATATION;

EID: 0036070438     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01016.2001     Document Type: Article

References (35)

1. Isozymes of the Na-K-ATPase: Heterogeneity in structure, diversity in function
2. 42K efflux in rabbit and guinea-pig arterial muscle
3. Regulation of arterial tone by activation of calcium-dependent potassium channels
4. Studies on potassium induced coronary dilation in the isolated guinea pig heart
5. + ATPase α-subunits in rat arteries
6. 86Rb efflux and on contraction in the rat caudal artery
7. Elevation of intracellular calcium in smooth muscle causes endothelial cell generation of NO in arterioles
8. + in the rat isolated mesenteric artery
9. An indirect influence of phenylephrine on the release of endothelium-derived vasodilators in rat small mesenteric artery
10. Potassium does not mimic EDHF in rat mesenteric arteries
11. Charybdotoxin and apamin block EDHF in rat mesenteric artery if selectively applied to the endothelium
12. + is an endothelium-derived hyperpolarizing factor in rat arteries
13. Role of gap junctions in the responses to EDHF in rat and guinea-pig small arteries
14. Further investigation of endothelium-derived hyperpolarizing factor (EDHF) in rat hepatic artery: Studies using 1-EBIO and ouabain
15. Evidence that nitric oxide does not mediate the hyperpolarization and relaxation to acetylcholine in the rat small mesenteric artery
16. 86Rb efflux from isolated endothelial cells
17. 2+] in cerebral arteries of rat by membrane potential and intravascular pressure
18. + channels
19. Perivascular potassium and pH as determinants of local pial arterial diameter in cats. A microapplication study
20. Evidence against potassium as an endothelium-derived hyperpolarizing factor in rat mesenteric small arteries
21. Calcium-activated potassium channels in the endothelium of intact rat aorta
22. Ca) from smooth muscle cells isolated from the rabbit mesenteric artery
23. Sodium-potassium pump current in smooth muscle cells from mesenteric resistance arteries of the guinea-pig
24. + channels
25. Role of potassium in the regulation of systemic physiological function during exercise
26. i reduction and relaxation by norepinephrine, ET-1, and PMA
27. Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries
28. 2+ spark/STOC coupling and elevated blood pressure
29. +-induced hyperpolarization by phenylephrine in rat mesenteric artery: Relevance to studies of endothelium-derived hyperpolarizing factor
30. Incidence of myoendothelial gap junctions in the proximal and distal mesenteric arteries of the rat is suggestive of a role in endothelium-derived hyperpolarizing factor-mediated responses
31. Noradrenaline-induced depolarization is smaller in isobaric compared with isometric preparations of rat mesenteric small arteries
32. Characteristics and origin of myogenic response in isolated mesenteric arterioles
33. Effect of potassium channel blockers on L-NAME insensitive relaxations in rat small mesenteric arteries
34. Ca and 1-ethyl-2-benzimidazolinone evokes smooth muscle hyperpolarization in rat isolated mesenteric artery
35. Ca-channel blockade prevents sustained pressure-induced depolarization in rat mesenteric small arteries