Evolution of β-amyloid induced neuropathology: Magnetic resonance imaging and anatomical comparisons in the rodent hippocampus

Magnetic Resonance Materials in Physics, Biology and Medicine

Volumn 14, Issue 3, 2002, Pages 223-232

  Bhagat, Yusuf A ^a   Obenaus, André ^a,b   Richardson, J Steven ^c   Kendall, Edward J ^a  

^a ROYAL UNIVERSITY HOSPITAL   (Canada)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Amyloid 25 35; Alzheimer's disease; Apparent diffusion coefficients; Diffusion weighted imaging; Hippocampus; Neurodegeneration

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (25 35); AMYLOID BETA-PROTEIN (25-35); PEPTIDE FRAGMENT;

ADOLESCENT; ALZHEIMER DISEASE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN EDEMA; CELL DEATH; DIFFUSION COEFFICIENT; DIFFUSION WEIGHTED IMAGING; HIPPOCAMPUS; HISTOPATHOLOGY; INFLAMMATION; MALE; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATIVE STRESS; PATHOLOGICAL ANATOMY; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; QUANTITATIVE ANALYSIS; RAT; ANIMAL; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DISEASE COURSE; DRUG EFFECT; PATHOLOGY; REFERENCE VALUE; SENSITIVITY AND SPECIFICITY; SPRAGUE DAWLEY RAT; TIME;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMAL; COMPARATIVE STUDY; DIFFUSION MAGNETIC RESONANCE IMAGING; DISEASE PROGRESSION; HIPPOCAMPUS; MALE; MODELS, ANIMAL; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; ANIMALS;

ANIMALIA; RODENTIA;

EID: 0036069638     PISSN: 13528661     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1352-8661(02)00067-4     Document Type: Article

References (50)

1. Alzheimer's disease: Clinical and pathological characteristics
2. Structural correlates of cognitive deficits in a selected group of patients with Alzheimer's disease
3. Possible causes of Alzheimer's disease: Amyloid fragments, free radicals, and calcium homeostasis
4. Evolution of the neuropathology of Alzheimer's disease
5. Free radicals in neurotoxic actions of β-amyloid
6. Oxidative stress in the production and expression of neurotoxic β-amyloid
7. Actions of neurotoxic β-amyloid on calcium homeostasis and viability of PC 12 cells are blocked by antioxidants but not by calcium channel antagonists
8. Amyloid (1-40) effects on behavior and memory
9. Specificty of temporal amygdala atrophy in Alzheimer's disease: Quantitative assessment with magnetic resonance imaging
10. Quantitative computed tomography and magnetic resonance imaging in aging and Alzheimer's disease
11. Autopsy samples of Alzheimer's cortex show increased peroxidation in vitro
12. On the possible role of iron-induced free radical peroxidation in Alzheimer's disease
13. Amyloid associated free radical oxidative stress and neurotoxicity: Implications for Alzheimer's disease
14. Free radicals in the genesis of Alzheimer's disease
15. Electron leakage from the mitochondrial NADPH-adrenodoxin reductase-adrenodoxin-P450scc (cholesterol side chain cleavage) system
16. Cerebral changes and cerebrospinal fluid β-amyloid in Alzheimer's disease: A study with quantitative magnetic resonance imaging
17. In vivo quantification of brain volumes in subcortical vascular dementia and Alzheimer's disease
18. Increased water diffusion in cerebral white matter in Alzheimer's disease
19. Diffusion-weighted MR imaging of the hippocampus and temporal white matter in Alzheimer's disease
20. Diffusion-weighted magnetic resonance imaging in Alzheimer's disease
21. Evaluation of extra- and intracellular apparent diffusion in normal and globally ischemic rat brain via 19F NMR
22. The neurochemical and behavioral effects of β-amyloid peptide (25-35)
23. Amyloid induced reduction in synaptic transmission is reversed by inhibitors of nitric oxide synthase
24. Effects of doses of fragment (25-35) of β-amyloid peptide on behavior in rats
25. Laterality in the histological effects of amyloid-β 25-35 into the amygdala of young Fischer rats: Behavioral, neurochemical, and time dependent histopathological effects
26. Co-injection of β-amyloid with ibotenic acid induces synergistic loss of rat hippocampal neurons
27. Conformations of synthetic β peptides in solid state and in aqueous solution: Relation to toxicity in PC12 cells
28. Promotion of transition metal-induced reactive oxygen species formation by β-amyloid
29. Amyloid peptide fragment 31-35 induces apoptosis in cultured cortical neurons
30. Intahippocampal injections of β-amyloid fragments in rats: Neurodegeneration visualized using MRI
31. MR imaging of intravoxel incoherent motions: Applications to diffusion and perfusion in neurologic disorders
32. Rapid alterations in diffusion-weighted images with anatomic correlates in a rodent model of status epilepticus
33. Loss of glutamate decarboxylase mRNA-containing neurons in the rat dentate gyrus following pilocarpine induced seizures
34. On the binding of congo red by amyloid
35. Extracellular space structure revealed by diffusion analysis
36. Effects of injected Alzheimer β-amyloid cores in the rat brain
37. Phagocytosis and deposition of vascular β-amyloid in rat brains injected with Alzheimer β-amyloid
38. Intracerebral β-amyloid (25-35) produces tissue damage: Is it neurotoxic?
39. In vivo neurotoxicity of β-amyloid [β(1-40)] and the β(25-35) fragment
40. The measurement of diffusion and perfusion in biological systems using magnetic resonance imaging
41. Long-term changes in the aggregation state and toxic effects of β-amyloid injected into the rat brain
42. Local and distant histopathological effects of unilateral amyloid-β 25-35 injections into the amygdala of young F344 rats
43. Laterality in the histological effects of injections of amyloid-β 25-35 into the amygdala of young Fischer rats
44. Early perfusion after controlled cortical impact in rats: Quantification by arterial spin-labeled MRI and the influence of spin-lattice relaxation time heterogeneity
45. Hippocampal region
46. Changes in excitatory and inhibitory circuits of the rat hippocampus 12-14 months after complete forebrain ischemia
47. Chronic cerebrovascular insufficiency induces dementia-like deficits in aged rats
48. Cerebral ischemia hypoxia: Discrepancy between apparent diffusion coefficients and histologic changes in rats