GabR, a member of a novel protein family, regulates the utilization of γ-aminobutyrate in Bacillus subtilis

Molecular Microbiology

Volumn 45, Issue 2, 2002, Pages 569-583

  Belitsky, Boris R ^a   Sonenshein, Abraham L ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRIC ACID; AMINOTRANSFERASE; BACTERIAL PROTEIN; SUCCINATE SEMIALDEHYDE DEHYDROGENASE;

ARTICLE; AUTOREGULATION; BACILLUS SUBTILIS; CHIMERA; CONTROLLED STUDY; DNA BINDING; GENE CONTROL; GENE LOCATION; GENE MUTATION; GENETIC CODE; NONHUMAN; OPERON; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; TRANSCRIPTION INITIATION;

4-AMINOBUTYRATE TRANSAMINASE; ALDEHYDE OXIDOREDUCTASES; AMINO ACID SEQUENCE; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES, BACTERIAL; CLONING, MOLECULAR; GAMMA-AMINOBUTYRIC ACID; GENE DELETION; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NITROGEN; OPERON; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE; TRANS-ACTIVATORS;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); POSIBACTERIA; PROKARYOTA;

EID: 0036062693     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2002.03036.x     Document Type: Article

References (54)

1. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
2. Integrator gene in Aspergillus nidulans
3. A method for the selection of deletion mutations in the L-proline catabolism gene cluster of Aspergillus nidulans
4. Identification of genes and gene products whose expression is activated during nitrogen-limited growth in Bacillus subtilis
5. Molecular analysis of two genes of the Escherichia coli gab cluster: Nucleotide sequence of the glutamate: Succinic semialdehyde transaminase gene (gabT) and characterization of the succinic semialdehyde dehydrogenase gene (gabD)
6. Biosynthesis of amino acids of the glutamate and aspartate families, alanine, and polyamines
7. Role and regulation of Bacillus subtilis glutamate dehydrogenase genes
8. Sites required for GltC-dependent regulation of Bacillus subtilis glutamate synthase expression
9. An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport
10. 4-Aminobutyrate (GABA) transporters from the amine-polyamine-choline superfamily: Substrate specificity and ligand recognition profile of the 4-aminobutyrate permease from Bacillus subtilis
11. Expression of a glutamate decarboxylase homologue is required for normal oxidative stress tolerance in Saccharomyces cerevisiae
12. Isolation and characterization of the lacA gene encoding β-galactosidase in Bacillus subtilis and a regulator gene lacR
13. Carbohydrate uptake and metabolism
14. Succinic semialdehyde dehydrogenases of Escherichia coli: Their role in the degradation of p-hydroxyphenylacetate and γ-aminobutyrate
15. Genetic analysis of the γ-aminobutyrate utilization pathway in Escherichia coli K-12
16. Expression of the Bacillus subtilis gabP gene is regulated independently in response to nitrogen and amino acid availability
17. Regulation of nitrogen metabolism in Bacillus subtilis: Vive la difference!
18. Nitrogen source utilization and its regulation
19. Bacillus subtilis 168 contains two differentially regulated genes encoding L-asparaginase
20. A target for carbon source-dependent negative regulation of the citB promoter of Bacillus subtilis
21. Chemo-enzymatic synthesis of 3-(2-naphthyl)-L-alanine by an aminotransferase from the extreme thermophile, Thermococcus profundus
22. A new family of bacterial regulatory proteins
23. Characterisation of Saccharomyces cerevisiae ARO8 and ARO9 genes encoding aromatic aminotransferases I and II reveals a new aminotransferase subfamily
24. Evolutionary recruitment of biochemically specialized subdivisions of Family I within the protein superfamily of aminotransferases
25. Pyridoxal phosphate-dependent enzymes
26. Genetic evidence for interaction of sigma A with two promoters in Bacillus subtilis
27. Rapid and efficient site-specific mutagenesis without phenotypic selection
28. The complete genome sequence of the gram-positive bacterium Bacillus subtilis
29. Isolation and characterization of kinC, a gene that encodes a sensor kinase homologous to the sporulation sensor kinases KinA and KinB in Bacillus subtilis
30. The pdx genetic marker adjacent to the chloramphenicol biosynthesis gene cluster in Streptomyces venezuelae ISP5230: Functional characterization
31. 'DNA Strider': A 'C' program for the fast analysis of DNA and protein sequences on the Apple Macintosh family of computers
32. Aminotransferases: Demonstration of homology and division into evolutionary subgroups
33. Catabolite repression mediated by the CcpA protein in Bacillus subtilis: Novel modes of regulation revealed by whole-genome analyses
34. Molecular organization of the Escherichia coli gab cluster: Nucleotide sequence of the structural genes gabD and gabP and expression of the GABA permease gene
35. Identification of sigma (B)-dependent genes in Bacillus subtilis using a promoter consensus-directed search and oligonucleotide hybridization
36. Global analysis of the general stress response of Bacillus subtilis
37. Genome-wide analysis of the general stress response in Bacillus subtilis
38. Mutations affecting the enzymes involved in the utilization of 4-aminobutyric acid as nitrogen source by the yeast Saccharomyces cerevisiae
39. Sources of nitrogen and their utilization
40. Molecular and genetic characterization of the rhizopine catabolism (mocABRC) genes of Rhizobium meliloti L5-30
41. Properties and functions of two succinic-semialdehyde dehydrogenases from Pseudomonas putida
42. Purification and properties of two succinic semialdehyde dehydrogenases from Klebsiella pneumoniae
43. DNA sequencing with chain-terminating inhibitors
44. Promoter-probe vectors for the analysis of divergently arranged promoters
45. Characterization of polyamine synthesis pathway in Bacillus subtilis 168
46. An Escherichia coli mutant defective in the NAD-dependent succinate semialdehyde dehydrogenase
47. A gene required for nutritional repression of the Bacillus subtilis dipeptide permease operon
48. New shuttle vectors for Bacillus subtilis and Escherichia coli which allow rapid detection of inserted fragments
49. TnrA, a transcription factor required for global nitrogen regulation in Bacillus subtilis
50. Mutational analysis of the TnrA-binding sites in the Bacillus subtilis nrgAB andgabP promoter regions
51. The 25 degrees-36 degrees region of the Bacillus subtilis chromosome: Determination of the sequence of a 146 kb segment and identification of 113 genes
52. Improved M13 phage cloning vectors and host strains: Nucleotide sequences of the M13mp18 and pUC19 vectors