An important role for protein kinase C-δ in human keratinocyte migration on dermal collagen

Experimental Cell Research

Volumn 273, Issue 2, 2002, Pages 219-228

  Li, Wei ^a,c   Nadelman, Celina ^a   Gratch, Noah S ^a   Li, Weiquin ^d   Chen, Mei ^a   Kasahara, Nori ^b   Woodley, David T ^a,c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^d GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; HYPOPHYSIS EXTRACT; LENTIVIRUS VECTOR; PROTEIN KINASE C DELTA;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; KERATINOCYTE; MIGRATION INHIBITION; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

BOVINAE; LENTIVIRUS;

EID: 0036061133     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2001.5422     Document Type: Article

References (37)

1. Re-epithelialization
2. Wound healing - Aiming for perfect skin regeneration
3. Cutaneous wound healing
4. Human keratinocyte locomotion: The effect of selected cytokines
5. Hypoxia increases human keratinocyte motility on connective tissue
6. The p38 MAPK/SAPK pathway is required for human keratinocyte migration on dermal collagen
7. Phosphorylation of focal adhesion kinase 9pp125FAK is increased in human keratinocytes induced to migrate by extracellular matrices
8. Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes
9. Expression of collagenase-3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase
10. Protein kinase Cδ
11. Loss of protein kinase C delta from human HaCaT keratinocytes upon ras transfection is mediated by TGF alpha
12. Transcripts encoding protein kinase C-alpha, -delta, -zeta, and -eta are expressed in basal and differentiating mouse keratinocytes in vitro and exhibit quantitative changes in neoplastic cells
13. Transgenic mice over-expressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion
14. Bryostatin 1 portects protein kinase C-δ from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester-induced differentiation
15. The SH2 and SH3 domains-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors
16. A high-titer lentiviral production system mediates efficient transduction of differentiated cells including beating cardiac myocytes
17. Characterization of a protein kinase C-delta (PKC-delta) ATP binding mutant. An inactive enzyme that competitively inhibits wild type PKC-delta enzymatic activity
18. Tyrosine phosphorylation of a 57-kDa protein in growth factor stimulated and transformed cells
19. The phargokinetic tracks of 3T3 cells
20. Epidermal growth factor (EGF) promotes human keratinocyte locomotion on collagen by increasing the alpha 2 integrin subunit
21. Rottlerin, a novel protein kinase inhibitor
22. Protein kinase C-delta, an important signaling molecule in the platelet-derived growth factor beta receptor pathway
23. Expression of an ATP binding mutant of PKC-delta inhibits Sis-induced transformation of NIH3T3 cells
24. Antisense oligodeoxynucleotide inhibition of delta protein kinase C expression accelerates induced differentiation of murine erythroleukaemia cells
25. The catalytic domain of protein kinase C-delta in reciprocal delta and epsilon chimeras mediates phorbol ester-induced macrophage differentiation of mouse promyelocytes
26. Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-delta subspecies
27. Protein kinase C delta inhibits the proliferation of vascular smooth muscle cells by suppressing G1 cyclin expression
28. Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity
29. Opposite effects of the overexpression of protein kinase C gamma and delta on the growth properties of human glioma cell line U251 MG
30. Enhancement of migration by protein kinase Calpha and inhibition of proliferation and cell cycle progression by protein kinase Cdelta in capillary endothelial cells
31. Activation of protein kinase Cdelta in human myeloid leukemia cells treated with 1-beta-D-arabinofuranosylcytosine
32. Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis
33. Tyrosine phosphorylation and stimulation of protein kinase C delta from porcine spleen by src in vitro. Dependence on the activated state of protein kinase C delta
34. Association of PKC delta and active Src in PMA-treated MCF-7 human breast cancer cells
35. Tyrosine phosphorylation of protein kinase C-delta in response to its activation
36. Stimulation of the platelet-derived growth factor beta receptor signaling pathway activates protein kinase C-delta
37. Nckβ regulates PDGF-stimulated actin polymerization in NIH 3T3 fibroblasts