Diet-induced mild hyperhomocysteinemia and increased salt intake diminish vascular endothelial function in a synergistic manner

Journal of Hypertension

Volumn 20, Issue 1, 2002, Pages 55-62

  Morita, Hiroyuki ^a   Saito, Yuichiro ^a   Kurabayashi, Masahiko ^a   Nagai, Ryozo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Blood pressure; Homocysteine; Oxidant; Salt; Vascular endothelial function

Indexed keywords

ACETYLCHOLINE; HOMOCYSTEINE; METHIONINE; NITRIC OXIDE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; ATHEROSCLEROSIS; BLOOD PRESSURE; CONTROLLED STUDY; DIET; DISEASE PREDISPOSITION; HYPERHOMOCYSTEINEMIA; LIPID BLOOD LEVEL; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; SALT INTAKE; SODIUM EXCRETION; VASCULAR ENDOTHELIUM;

EID: 0036059846     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-200201000-00009     Document Type: Article

References (33)

1. Disorders of transsulfuration
2. Homocysteine and coronary atherosclerosis
3. Hyperhomocysteinemia: An independent risk factor for vascular disease
4. A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians
5. Homocysteine as a risk factor for restenosis after coronary angioplasty
6. Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease
7. ACE and MTHFR gene polymorphisms: Genetic coronary risk factors relating to different aspects of pathophysiology
8. Methylenetetrahydrofolate reductase gene polymorphism and ischemic stroke in Japanese
9. Polymorphism of the methionine synthase gene: Association with homocysteine metabolism and late-onset vascular diseases in the Japanese population
10. Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease
11. Genetic analysis of the thermolabile variant of 5,10-methylenetetrahydrofolate reductase as a risk factor for ischemic stroke
12. Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury
13. Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia
14. Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans
15. Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in healthy adults
16. Dysfunction of nitric oxide mediation in isolated rat arterioles with methionine diet-induced hyperhomocysteinemia
17. Homocysteine-induced inhibition of endothelium-dependent relaxation in rabbit aorta: Role for superoxide anions
18. The pathogenesis of atherosclerosis: A perspective for the 1990s
19. Adaptation to increased dietary salt intake in the rat. Role of endogenous nitric oxide
20. Dietary sodium affects systemic and renal hemodynamic response to NO inhibition in healthy humans
21. Effects of sodium intake on the pressor and renal responses to nitric oxide synthesis inhibition in normotensive individuals with different sodium sensitivity
22. Pressure-independent contribution of sodium to large artery structure and function in hypertension
23. Dietary salt increases endothelial nitric oxide synthase and TGF-b1 in rat aortic endothelium
24. A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism
25. Isoprostanes: Potential markers of oxidant stress in atherothrombotic disease
26. Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression
27. Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection
28. Mass spectrometry of prostanoids: F2-isoprostanes produced by non-cyclooxygenase free radical-catalyzed mechanism
29. Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase
30. Salt intake and plasma atrial natriuretic peptide and nitric oxide in hypertension
31. Study on the relationship between plasma nitrite and nitrate level and salt sensitivity in human hypertension: Modulation of nitric oxide synthesis by salt intake
32. High homocysteine levels are independently related to isolated systolic hypertension in older adults
33. Primary hypertension: Pathogenesis