Intracellular rate-limiting steps of gene transfer using glycosylated polylysines in cystic fibrosis airway epithelial cells

Gene Therapy

Volumn 9, Issue 15, 2002, Pages 1000-1007

  Grosse, S ^a,b   Tremeau Bravard, A ^c   Aron, Y ^a   Briand, P ^b   Fajac, I ^a  

^a AP HP Université Paris V ^*  (France)

^b INSTITUT COCHIN   (France)

^c INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Cystic fibrosis; Endosomes; Glycosylated polylysine; Intracellular trafficking; Lysosomes; Transcription

Indexed keywords

FLUORESCEIN; LAMIN A; LAMIN C; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; PLASMID DNA; POLYLYSINE; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BIOTINYLATION; CELL NUCLEUS; COMPLEX FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYSTIC FIBROSIS; ENDOSOME; EPITHELIUM CELL; GENETIC PROCEDURES; GLYCOSYLATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LYSOSOME; NONVIRAL GENE DELIVERY SYSTEM; NUCLEASE S1 TRANSCRIPTION ASSAY; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; TRANSCRIPTION INITIATION;

CYSTIC FIBROSIS; EPITHELIAL CELLS; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; HUMANS; LACTOSE; LUCIFERASES; LYSINE; MANNOSE; PLASMIDS; RESPIRATORY MUCOSA; SECOND MESSENGER SYSTEMS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0036046098     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301768     Document Type: Article

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