Antimalarial drugs inhibit the acetylcholine-receptor-operated potassium current in atrial myocytes

Heart Lung and Circulation

Volumn 11, Issue 2, 2002, Pages 112-116

  Hara, Yukio ^a   Kizaki, Keiichiro ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Acetylcholine receptor operated potassium current; Antimalarial drug; Cardiotoxicity; Pharmacology

Indexed keywords

ANTIMALARIAL AGENT; CARBACHOL; CHLOROQUINE; CHOLINERGIC RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE TRIPHOSPHATE; HALOFANTRINE; LIGAND; MUSCARINIC RECEPTOR; NUCLEIC ACID BINDING PROTEIN; POTASSIUM CHANNEL; PRIMAQUINE; PYRIMETHAMINE; QUINIDINE;

ANIMAL TISSUE; ANTICHOLINERGIC EFFECT; ARTICLE; CARDIOTOXICITY; CELL ISOLATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ELECTROCARDIOGRAPHY; GUINEA PIG; HEART ATRIUM; HEART MUSCLE CELL; HEART VENTRICLE ARRHYTHMIA; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; QT INTERVAL;

EID: 0036042501     PISSN: 14439506     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1443-9506.2002.00128.x     Document Type: Article

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