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Volumn 28, Issue 2, 2002, Pages 267-277

Linear free-energy relationships and the dynamics of gating in the acetylcholine receptor channel: A φ-value analysis of an allosteric transition at the single-molecule level

Author keywords

Br nsted plots; Ion channels; Nicotinic receptors; Transition state

Indexed keywords

CHOLINERGIC RECEPTOR; ION; ION CHANNEL; LIGAND;

EID: 0036040016     PISSN: 00920606     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1019935832427     Document Type: Conference Paper
Times cited : (6)

References (15)
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    • On the application of 'A Plausible Model' of allosteric proteins to the receptor for acetylcholine
    • (1967) J. Theor. Biol. , vol.16 , pp. 306-320
    • Karlin, A.1
  • 5
    • 0034100847 scopus 로고    scopus 로고
    • Kinetic mechanistic, and structural aspects of unliganded gating of acetylcholine receptor channels. A single-channel study of M2 12′ mutants
    • (2000) J. Gen. Physiol. , vol.115 , pp. 621-635
    • Grosman, C.1    Auerbach, A.2
  • 10
    • 0028868995 scopus 로고
    • The structure of the transition state for folding of chymotrypsin inhibitor 2 analyzed by protein engineering methods: Evidence for a nucleation-condensation mechanism for protein folding
    • (1995) J. Mol. Biol. , vol.254 , pp. 260-288
    • Itzhaki, L.S.1    Otzen, D.E.2    Fersht, A.R.3
  • 12
    • 0000288714 scopus 로고
    • Parameters for the description of transition states
    • (1953) Science , vol.117 , pp. 340-341
    • Leffler, J.E.1
  • 13
    • 0034064135 scopus 로고    scopus 로고
    • Independent asymmetric contribution of the second transmembrane segment 12′ residues to diliganded gating of acetylcholine receptor channels: A single-channel study with choline as the agonist
    • (2000) J. Gen. Physiol. , vol.115 , pp. 637-651
    • Grosman, C.1    Auerbach, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.