The role of pre-ischaemic application of the nitric oxide donor spermine/nitric oxide complex in enhancing flap survival in a rat model

British Journal of Plastic Surgery

Volumn 55, Issue 5, 2002, Pages 430-433

  Küntscher, Markus V ^a   Juran, Sebastian ^a   Menke, Henrik ^a   Erdmann, Detlev ^a   Germann, Günter ^a   Gebhard, Martha Maria ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Flap; Ischaemia reperfusion injury; Ischaemic preconditioning; Nitric oxide

Indexed keywords

NITRIC OXIDE; NITRIC OXIDE DONOR; SPERMINE;

ADIPOCUTANEOUS FLAP; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONDITIONING; CONTROLLED STUDY; DRUG HALF LIFE; DRUG RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SKIN FLAP SURVIVAL; TISSUE FLAP; TISSUE NECROSIS;

EID: 0036038137     PISSN: 00071226     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjps.2002.3871     Document Type: Article

References (39)

1. Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
2. Critical role for nitric oxide signaling in cardiac and neuronal ischemic preconditioning and tolerance
3. Pharmacological modulation, preclinical studies, and new clinical features of myocardial ischemic preconditioning
4. Preconditioning: Effect upon lesion modulation in warm liver ischemia
5. Ischemic preconditioning improves liver microcirculation after ischemia/reperfusion
6. Ischaemia-reperfusion injury in rat kidney: The effect of preconditioning
7. Preconditioning: A new technique for improved muscle flap survival
8. Acute ischemic preconditioning of skeletal muscle prior to flap elevation augments muscle-flap survival
9. Ischemic preconditioning improves the survival of skin and myocutaneous flaps in a rat model
10. Ischemic preconditioning versus intermittent reperfusion to improve blood flow to a vascular isolated skeletal muscle flap of rats
11. Attenuation of vasospasm and capillary no-reflow by ischemic preconditioning in skeletal muscle
12. The preconditioned TRAM flap: Preliminary clinical experience
13. Ischemic preconditioning by brief extremity ischemia before flap ischemia in a rat model
14. Protective effect of preconditioning on the injury associated to hepatic ischemia-reperfusion in the rat: Role of nitric oxide and adenosine
15. Liver ischemic preconditioning is mediated by the inhibitory action of nitric oxide on endothelin
16. Complexes of nitric oxide with nucleophiles as agents for the controlled biological release of nitric oxide: Antiplatelet effect
17. Complexes of nitric oxide with nucleophiles as agents for the controlled biological release of nitric oxide: Hemodynamic effect in the rabbit
18. Toward a better understanding of the metabolic effects of ischemic preconditioning in humans
19. Improved free musculocutaneous flap survival with induction of heat shock protein
20. Ischemic preconditioning of the liver in rats: Implications of heat shock protein induction to increase tolerance of ischemia-reperfusion injury
21. Transient adenosine infusion before ischemia and reperfusion protects against metabolic damage in pig hearts
22. Effector mechanism of adenosine in acute ischemic preconditioning of skeletal muscle against infarction
23. Role of ATP-sensitive K+ channels in ischemic preconditioning of skeletal muscle against infarction
24. Evidence for an essential role of cyclooxygenase-2 as a mediator of the late phase of ischemic preconditioning in mice
25. Bradykinin mediates cardiac preconditioning at a distance
26. Nitric oxide donors improve gut function after prolonged hypothermic ischemia
27. Use of a nitric oxide precursor to protect pig myocutaneous flaps from ischemia-reperfusion injury
28. The pathophysiology of ischaemic preconditioning
29. NO news is good news
30. Nitric oxide, nitrates and ischaemic preconditioning
31. Ischemic preconditioning increases iNOS transcript levels in conscious rabbits via a nitric oxide-dependent mechanism
32. Nitric oxide and myocardial ischemic preconditioning
33. Nitric oxide donors regulate nitric oxide synthase in bovine pulmonary artery endothelium
34. Analysis of nitric oxide activity in prevention of reperfusion injury
35. Initiation of microvascular protection by nitric oxide in late preconditioning
36. The influence of skin flap ischemia on serum nitric oxide concentrations
37. Secondary ischemic tolerance improved by administration of L-NAME in rat flaps
38. New nitric oxide-releasing zwitterions derived from polyamines
39. Complexes of NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects