Multivariate cluster analysis of a human hepatic cytochrome P450 database

European Journal of Clinical Pharmacology

Volumn 58, Issue 8, 2002, Pages 559-562

  Sy, Sherwin K B ^a   Johnston, James A ^b   Class, Christopher F ^c   Roberts, Eve A ^d   Kalow, Werner ^e   Tang, Bing Kou ^e  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c Innaphase Corporation   (United States)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cluster analysis; Cytochrome P450; Demography; Phenotype; Probe

Indexed keywords

CAFFEINE; CHLORZOXAZONE; CYTOCHROME P450; ETHOXYRESORUFIN DEETHYLASE; ISOENZYME; PHENACETIN O DEETHYLASE; TESTOSTERONE; CYP3A PROTEIN, HUMAN; CYTOCHROME P450 1A2; CYTOCHROME P450 2E1;

ADOLESCENT; ADULT; AGE; CLUSTER ANALYSIS; COMPUTER PROGRAM; COVARIANCE; DATA BASE; DEMOGRAPHY; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME METABOLISM; ENZYME SUBSTRATE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LETTER; LINEAR REGRESSION ANALYSIS; LIVER; LIVER MICROSOME; MALE; MATHEMATICAL PARAMETERS; MOLECULAR PROBE; MORPHOLOGICAL TRAIT; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SEX DIFFERENCE; SPECTROMETRY; STATISTICAL MODEL; ALGORITHM; CHILD; ENZYMOLOGY; METABOLISM;

ADOLESCENT; ADULT; AGE FACTORS; ALGORITHMS; CHILD; CLUSTER ANALYSIS; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HUMANS; MALE; MICROSOMES, LIVER; MULTIVARIATE ANALYSIS; SEX FACTORS;

EID: 0036027326     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-002-0515-9     Document Type: Letter

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