Histopathology of lupus-like nephritis in Dnase1-deficient mice in comparison to NZB/W F1 mice

Lupus

Volumn 11, Issue 8, 2002, Pages 514-527

  Jacob, M ^a   Napirei, M ^a   Ricken, A ^a   Dixkens, C ^a   Mannherz, H G ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

ANA; Dnase1; NZB W F1 mice; SLE

Indexed keywords

ANTINUCLEAR ANTIBODY; DEOXYRIBONUCLEASE I;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CHROMOSOME 16; CLINICAL FEATURE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE CLASSIFICATION; DISEASE PREDISPOSITION; DISEASE SEVERITY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCUS; GENE MAPPING; GENETIC SUSCEPTIBILITY; HISTOPATHOLOGY; IMMUNE COMPLEX DISEASE; KNOCKOUT MOUSE; LUPUS ERYTHEMATOSUS NEPHRITIS; MALE; MESANGIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE; THROMBOCYTE AGGREGATION; ANIMAL; ANTIGEN ANTIBODY COMPLEX; C57BL MOUSE; DISEASE MODEL; GENETICS; GLOMERULUS; IMMUNOLOGY; MICROTOMY; MOUSE MUTANT; NEW ZEALAND BLACK MOUSE; PATHOLOGY; ULTRASTRUCTURE;

ANIMAL; ANTIGEN-ANTIBODY COMPLEX; COMPARATIVE STUDY; DEOXYRIBONUCLEASE I; DISEASE MODELS, ANIMAL; FEMALE; KIDNEY GLOMERULUS; LUPUS NEPHRITIS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED NZB; MICE, KNOCKOUT; MICROTOMY; SUPPORT, NON-U.S. GOV'T; ANIMALS;

EID: 0036024628     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1191/0961203302lu242oa     Document Type: Article

References (40)

1. The genetics of systemic lupus erythematosus
2. Susceptibility to lupus nephritis in the NZB/W model system
3. Etiopathogenesis of systemic lupus erythematosus
4. Lupus, Dnase and defective disposal of cellular debris
5. Homozygous Clq deficiency causes glomerulonephritis associated with multiple apoptotic bodies
6. Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity
7. Features of systemic lupus erythematosus in Dnase 1-deficient mice
8. Relevance of systemic lupus erythematosus nephritis animal models to human disease
9. The natural history of the NZB/W F1 hybrid mouse: A laboratory model of systemic lupus erythematosus
10. The immunology and pathology of NZB mice
11. The value of electron microscopy in the diagnosis and clinical management of lupus nephritis
12. Robertsonian house mouse population in Tunesia: A karyological and biochemical study
13. Establishment of permanent wild-mouse cell lines with readily identifiable marker chromosomes
14. Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries
15. Sequence analysis of the conserved protamine gene cluster shows that it contains a fourth expressed gene
16. Chromosomal assignment of the human deoxyribonuclease I gene, DNASE1 (DNL1), to band 16p13.3 using the polymerase chain reaction
17. A new function for an old enzyme: The role of Dnase I in apoptosis
18. Nucleosomes are major T and B cell autoantigens in systemic lupus erythematosus
19. Anti-DNA antibodies and their relationship with anti-histone and anti-nucleosome specificities
20. Role of nucleosomes for induction and glomerular binding of autoantibodies in lupus nephritis
21. Lupus anti-DNA autoantibodies cross-react with a glomerular structural protein: A case for tissue injury by molecular mimicry
22. Systemischer lupus erythematosus und antiphospholipidsyndrom
23. Correlation among WHO classes, histomorphologic patterns of glomerulonephritis and glomerular immune deposits in SLE
24. The pathogenesis and prognosis of lupus nephritis: Information from repeat renal biopsy
25. Study of lupus nephritis: Its classification and the significance of subendothelial deposits
26. Lupus nephritis. Electron-dense and immunofluorescent deposits and their correlation with proteinuria and renal function
27. Ultrastructure of the renal glomerular hematoxylin bodies
28. Multiplex inheritance of component phenotypes in a murine model of lupus
29. The pathogenesis of autoimmunity in New Zealand mice
30. An ultrastructural study of spontaneous lupus nephritis in the NZB/BL-NZW mouse
31. NZB/NZW mice as a model of systemic lupus erythematosus
32. Pathogenesis of lupus nephritis: A review
33. Increased steady-state levels of mRNA coding for extracellular matrix components in kidneys of NZB/W F1 mice
34. Immunogold labelling of cytokines in glomeruli in children with various renal diseases
35. SLE nephritis: An ultrastructural immunogold study to evaluate the relationship between immune complexes and the basement membrane components type IV collagen, fibronectin and heparan sulphate proteoglycans
36. Measurement of deoxyribonuclease I (DNase) in the serum and urine of systemic lupus erythematosus (SLE)-prone NZB/NZW mice by a new radial enzyme diffusion assay
37. The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant DNase and dexamethasone
38. 1mice
39. Systemic lupus erythematosus
40. Mutation of DNASE1 in people with systemic lupus erythematosus