Perlecan participates in proliferation activation of quiescent Drosophila neuroblasts

Developmental Dynamics

Volumn 224, Issue 4, 2002, Pages 403-412

  Voigt, Aaron ^a   Pflanz, Ralf ^a   Schäfer, Ulrich ^a   Jäckle, Herbert ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

Drosophila perlecan; Heparan sulfate proteoglycan; Neuroblast proliferation; Optic lobe formation; Signal

Indexed keywords

GLYCOPROTEIN; PROTEOHEPARAN SULFATE; ANACHRONISM PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; PERLECAN; TROL PROTEIN, DROSOPHILA;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; DROSOPHILA; EXTRACELLULAR MATRIX; NEUROBLAST; NONHUMAN; OPTIC LOBE; PRIORITY JOURNAL; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CYTOLOGY; DROSOPHILA MELANOGASTER; EMBRYONIC STRUCTURES; FEMALE; GENE EXPRESSION REGULATION; GENETIC RECOMBINATION; GENETIC TRANSCRIPTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HISTOLOGY; IN SITU HYBRIDIZATION; METABOLISM; MOLECULAR GENETICS; MOUSE; NERVE CELL; OOCYTE DEVELOPMENT; PHYSIOLOGY; PRENATAL DEVELOPMENT; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; STEM CELL;

AMINO ACID SEQUENCE; ANIMAL; CELL DIVISION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EMBRYONIC STRUCTURES; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOPROTEINS; HEPARAN SULFATE PROTEOGLYCAN; IN SITU HYBRIDIZATION; MICE; MOLECULAR SEQUENCE DATA; NEURONS; OOGENESIS; OPTIC LOBE; PROTEIN STRUCTURE, TERTIARY; RECOMBINATION, GENETIC; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; STEM CELLS; SUPPORT, NON-U.S. GOV'T; TRANSCRIPTION, GENETIC; ANIMALS; HEPARAN SULFATE PROTEOGLYCANS;

MAMMALIA;

EID: 0036022254     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/dvdy.10120     Document Type: Article

References (64)

1. The genome sequence of Drosophila melanogaster
2. The molecular basis for metameric pattern in the Drosophila embryo
3. Perlecan is essential for cartilage and cephalic development
4. Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis
5. Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless
6. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
7. The C-terminal domain V of Perlecan promotes beta1 integrin-mediated cell adhesion, binds heparin, nidogen and fibulin-2 and can be modified by glycosaminoglycans
8. Regulation of synapse structure and function by the Drosophila tumor suppressor gene dlg
9. Expression of cyclin E or DP/E2F rescues the G1 arrest of trol mutant neuroblasts in the Drosophila larval central nervous system
10. Structural characterization of the complete human Perlecan gene and its promoter
11. Establishment of a cell line from the EHS tumor: Biosynthesis of basement membrane constituents and characterization of a hybrid proteoglycan containing heparan and chondroitin sulfate chains
12. Control of proliferation activation in quiescent neuroblasts of the Drosophila central nervous system
13. Activation of neuroblast proliferation in explant culture of the Drosophila larval CNS
14. l(1)trol and l(1)devl, loci affecting the development of the adult central nervous system in Drosophila melanogaster
15. The Drosophila anachronism locus: A glycoprotein secreted by glia inhibits neuroblast proliferation
16. The FlyBase database of the Drosophila Genome Projects and community literature
17. Perlecan domain V of Drosophila melanogaster. Sequence, recombinant analysis and tissue expression
18. The embryonic development of the Drosophila visual system
19. mushroom body defect, a gene involved in the control of neuroblast proliferation in Drosophila, encodes a coiled-coil protein
20. DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila
21. Developmental expression of perlecan during murine embryogenesis
22. Genes expressed in the ring gland, the major endocrine organ of Drosophila melanogaster
23. Isolation of a heparan sulfate-containing proteoglycan from basement membrane
24. Multicolor whole-mount in situ hybridisation
25. Protein family classification based on searching a database of blocks
26. Proliferation pattern of postembryonic neuroblasts in the brain of Drosophila melanogaster
27. The Drosophila mushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells
28. dally, a Drosophila glypican, controls cellular responses to the TGF-β-related morphogen
29. The anatomy and function of a segment of the X-chromosome of Drosophila melanogaster
30. Human basement membrane heparan sulfate proteoglycan core protein: A 467-kD protein containing multiple domains resembling elements of the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor
31. eve and ftz regulate a wide array of genes in blastoderm embryos: The selector homeoproteins directly or indirectly regulate most genes in Drosophila
32. Specificity of gene action during central nervous system development in Drosophila melanogaster: Analysis of the lethal (1) optic ganglion reduced locus
33. Identification and behavior of epithelial stem cells in the Drosophila ovary
34. Early events in mammalian craniofacial morphogenesis
35. Perlecan, the large low-density proteoglycan of basement membranes: Structure and variant forms
36. The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule
37. Separation of hematopoietic stem cells into two populations and their characterization
38. Drosophila homeobox gene eve enhances trol, an activator of neuroblast proliferation in the larval CNS
39. even skipped is required to produce a trans-acting signal for larval neuroblast proliferation that can be mimicked by ecdysone
40. Specificities of heparan sulphate proteoglycans in developmental processes
41. Genetic and physical linkage of exogenous sequences in transformed cells
42. Mapping and identification of essential gene functions on the X-chromosome of Drosophila
43. Structural basis for FGF receptor dimerization and activation
44. The origin of postembryonic neuroblasts in the ventral nerve cord of Drosophila melanogaster
45. Normal function of the mushroom body defect gene of Drosophila is required for the regulation of the number and proliferation of neuroblasts
46. Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction
47. The use of maternally coded gene products in Drosophila
48. A stable genomic source of P element transposase in Drosophila melanogaster
49. UNC-52/perlecan isoform diversity and function in Caenorhabditis elegans
50. A modular misexpression screen in Drosophila detecting tissue-specific phenotypes
51. A Drosophila complementary DNA resource
52. Genetic dissection of proteoglycan function in Drosophila and C elegans
53. Glycosylation events and patterning
54. Resting and activated subsets of mouse multipotent hematopoietic stem cells
55. Human CD34+ HLA-DR- bone marrow cells contain progenitor cells capable of self-renewal, multilineage differentiation, and long-term in vitro hematopoiesis
56. Wingless gradient formation in the Drosophila wing
57. The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation
58. A non-radioactive in situ hybridisation method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback
59. Proteoglycans of basement membranes
60. The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension
61. Spatial and temporal patterns of neurogenesis in the central nervous system of Drosophila melanogaster
62. The cell-surface proteoglycan Dally regulates Wingless signal in Drosophila
63. Patterns of cell division and cell movement in the formation of the imaginal nervous system in Drosophila melanogaster
64. The development and function of the female germ line in Drosophila melanogaster: A cell lineage study