A 10-Mb paracentric inversion of chromosome arm 2p inactivates MSH2 and is responsible for hereditary nonpolyposis colorectal cancer in a North-American kindred

Genes Chromosomes and Cancer

Volumn 35, Issue 1, 2002, Pages 49-57

  Wagner, Anja ^a,b   Van Der Klift, Heleen ^a   Franken, Patrick ^a   Wijnen, Juul ^a   Breukel, Cor ^a   Bezrookove, Vladimir ^a   Smits, Ron ^a   Kinarsky, Yulia ^c   Barrows, Alicia ^c   Franklin, Barbara ^c   Lynch, Jane ^c   Lynch, Henry ^c   Fodde, Riccardo ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^c CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ALLELE; ALLELISM; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CASE REPORT; CHROMOSOME 2P; COLORECTAL CANCER; DIAGNOSTIC VALUE; ENDOMETRIUM TUMOR; FRAMESHIFT MUTATION; GASTROINTESTINAL TUMOR; GENE DELETION; GENE IDENTIFICATION; GENE INSERTION; GENE LOCUS; GENE MUTATION; GENE REARRANGEMENT; GENETIC PREDISPOSITION; HUMAN; HYBRID CELL; LYMPHOCYTE ACTIVATION; MALE; MARKER GENE; MISSENSE MUTATION; MSH2 GENE; NONSENSE MUTATION; NORTH AMERICA; PARACENTRIC CHROMOSOME INVERSION; PATHOGENICITY; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOUTHERN BLOTTING; URINARY TRACT TUMOR; WESTERN BLOTTING; ADULT; ANIMAL; CHROMOSOME 2; CHROMOSOME ANALYSIS; CHROMOSOME INVERSION; COLORECTAL TUMOR; DRUG ANTAGONISM; ENZYMOLOGY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION PROFILING; GENE SILENCING; GENETICS; MIDDLE AGED; MOUSE; PEDIGREE;

ADENOSINETRIPHOSPHATASE; ADULT; AGED; ANIMAL; BLOTTING, SOUTHERN; CHROMOSOMES, HUMAN, PAIR 2; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; CYTOGENETIC ANALYSIS; FEMALE; GENE EXPRESSION PROFILING; GENE SILENCING; HUMAN; HYBRID CELLS; IN SITU HYBRIDIZATION, FLUORESCENCE; INVERSION (GENETICS); MALE; MICE; MIDDLE AGE; PEDIGREE; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; SUPPORT, NON-U.S. GOV'T; ADENOSINE TRIPHOSPHATASES; ANIMALS; DNA-BINDING PROTEINS; HUMANS; INVERSION, CHROMOSOME; MIDDLE AGED; MUTS HOMOLOG 2 PROTEIN;

RODENTIA;

ADENOSINE TRIPHOSPHATASE; DNA BINDING PROTEIN; MSH2 PROTEIN, HUMAN; MSH2 PROTEIN, MOUSE; ONCOPROTEIN; PROTEIN MSH2;

EID: 0036022069     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/gcc.10094     Document Type: Article

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