Effect of hyperosmolar mannitol on convection-enhanced delivery into the rat brain stem

Journal of Neuro-Oncology

Volumn 58, Issue 3, 2002, Pages 187-192

  Sandberg, David I ^a,b   Edgar, Mark A ^a   Souweidane, Mark M ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Brain stem tumor; Convection enhanced delivery; Diffuse pontine glioma; Hyperosmolar mannitol; Local delivery

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE DEXTRAN; MANNITOL; SODIUM CHLORIDE; DEXTRAN; DRUG DERIVATIVE; FLUORESCEIN ISOTHIOCYANATE; ISOTONIC SOLUTION;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN STEM; BRAIN STEM TUMOR; CANNULATION; COMPUTER; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG BRAIN LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFECT; DRUG INFUSION; FLUORESCENCE; GLIOMA; HYPEROSMOLARITY; ILLUMINATION; IMAGE ANALYSIS; MALE; NEUROLOGIC DISEASE; NONHUMAN; PONS; POSTOPERATIVE COMPLICATION; RAT; SAFETY; STATISTICAL SIGNIFICANCE; TRIGEMINAL NUCLEUS; ULTRAVIOLET RADIATION; ANIMAL; BRAIN; IMAGE PROCESSING; INTRAPERITONEAL DRUG ADMINISTRATION; METABOLISM; OSMOLARITY; SPINAL CORD; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

ANIMAL; BRAIN; DEXTRANS; DRUG DELIVERY SYSTEMS; FLUORESCEIN-5-ISOTHIOCYANATE; IMAGE PROCESSING, COMPUTER-ASSISTED; INJECTIONS, INTRAPERITONEAL; ISOTONIC SOLUTIONS; MALE; MANNITOL; MICROSCOPY, CONFOCAL; OSMOLAR CONCENTRATION; PONS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHLORIDE; SPINAL CORD; SUPPORT, NON-U.S. GOV'T; TISSUE DISTRIBUTION; ULTRAVIOLET RAYS; ANIMALS;

EID: 0036020495     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016213315548     Document Type: Article

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