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Volumn 2, Issue 1, 2002, Pages 31-42

Phase I radioimmunotherapy trial with iodine-131-labeled humanized MN-14 anti-carcinoembryonic antigen monoclonal antibody in patients with metastatic gastrointestinal and colorectal cancer

Author keywords

Carcinoembryonic antigen; Dosimetry; Humanized antibody; Radioimmunotherapy; Tumor targeting

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY MN 14; MONOCLONAL ANTIBODY MN-14; IMMUNOGLOBULIN G; IODINE 131; UNCLASSIFIED DRUG;

EID: 0036018888     PISSN: 15330028     EISSN: None     Source Type: Journal    
DOI: 10.3816/CCC.2002.n.009     Document Type: Article
Times cited : (50)

References (58)
  • 2
  • 8
    • 0035104782 scopus 로고    scopus 로고
    • Update of clinical trials with edrecolomab: A monoclonal antibody therapy for colorectal cancer
    • (2001) Semin Oncol , vol.28 , pp. 25-30
    • Haller, D.G.1
  • 9
    • 0032438053 scopus 로고    scopus 로고
    • Dose escalation trial of indium-111-labeled anti-carcinoembryonic antigen chimeric monoclonal antibody (chimeric T84.66) in presurgical colorectal cancer patients
    • (1998) J. Nucl. Med , vol.39 , pp. 2097-2104
    • Wong, J.Y.1    Chu, D.Z.2    Yamauchi, D.3
  • 11
    • 0031860807 scopus 로고    scopus 로고
    • Radioimmunoscintigraphy of recurrent, metastatic, or occult colorectal cancer with technetium 99m-labeled totally human monoclonal antibody 88BV59: Results of pivotal, phase III multicenter studies
    • (1998) J. Clin. Oncol , vol.16 , pp. 1777-1787
    • Serafini, A.N.1    Klein, J.L.2    Wolff, B.G.3
  • 15
    • 0028809274 scopus 로고
    • Carcinoembryonic antigen as a target cancer antigen for radiolabeled antibodies: Prospects for cancer imaging and therapy
    • (1995) Tumour Biol , vol.16 , pp. 62-73
    • Goldenberg, D.M.1
  • 16
    • 9444289885 scopus 로고    scopus 로고
    • Clinical utility of external immunoscintigraphy with the IMMU-4 technetium-99m Fab' antibody fragment in patients undergoing surgery for carcinoma of the colon and rectum: Results of a pivotal, phase III trial
    • The Immunomedics Study Group
    • (1996) J. Clin. Oncol , vol.14 , pp. 2295-2305
    • Moffat, F.L.1    Pinsky, C.M.2    Hammershaimb, L.3
  • 17
    • 0031446131 scopus 로고    scopus 로고
    • Use of carcinoembryonic antigen radioimmunodetection and computed tomography for predicting the resectability of recurrent colorectal cancer
    • (1997) Ann. Surg , vol.226 , pp. 621-631
    • Hughes, K.1    Pinsky, C.M.2    Petrelli, N.J.3
  • 22
    • 0020701108 scopus 로고
    • Immunological heterogeneity of carcinoembryonic antigen: Antigenic determinants on carcinoembryonic antigen distinguished by monoclonal antibodies
    • (1983) Cancer Res , vol.43 , pp. 686-692
    • Primus, F.J.1    Newell, K.D.2    Blue, A.3
  • 25
    • 0031750281 scopus 로고    scopus 로고
    • Therapeutic efficacy and dose-limiting toxicity of Auger-electron vs. Beta emitters in radioimmunotherapy with internalizing antibodies: Evaluation of 125I- vs. 131I-labeled CO17-1A in a human colorectal cancer model
    • (1998) Int. J. Cancer , vol.76 , pp. 738-748
    • Behr, T.M.1    Sgouros, G.2    Vougiokas, V.3
  • 29
    • 0032741274 scopus 로고    scopus 로고
    • Radioimmunotherapy of small volume disease of colorectal cancer metastatic to the liver: Preclinical evaluation in comparison to standard chemotherapy and initial results of a phase I clinical study
    • (1999) Clin. Cancer Res , vol.5 , pp. 3232s-3242s
    • Behr, T.M.1    Salib, A.L.2    Liersch, T.3
  • 32
    • 0028786364 scopus 로고
    • Evaluation of a complementarity-determining region-grafted (humanized) anti-carcinoembryonic antigen monoclonal antibody in preclinical and clinical studies
    • (1995) Cancer Res , vol.55 , pp. 5935s-5945s
    • Sharkey, R.M.1    Juweid, M.2    Shevitz, J.3
  • 38
    • 0030002992 scopus 로고    scopus 로고
    • MIRDOSE: Personal computer software for internal dose assessment in nuclear medicine
    • (1996) J. Nucl. Med , vol.37 , pp. 538-546
    • Stabin, M.G.1
  • 41
    • 0009685824 scopus 로고    scopus 로고
    • Comparison of the modified geometric mean and buildup factor internal dosimetry techniques used for organ activity quantitation of 131I- and 90Y-labeled antibodies
    • (Abstract #79)
    • (2001) J. Nucl. Med , vol.42 , pp. 22
    • Yeldell, D.1    Mardirossian, G.2    Sharkey, R.M.3
  • 55
    • 18744424004 scopus 로고    scopus 로고
    • Radioimmunotherapy of small cell lung carcinoma with the two-step method using a bispecific anti-carcinoembryonic antigen/anti-diethylenetriaminepentaacetic acid (DTPA) antibody and trial
    • (1999) Clin. Cancer Res , vol.5 , pp. 3259s-3267s
    • Vuillez, J.P.1    Kraeber-Bodere, F.2    Moro, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.