Increase of nucleotidase activities in rat blood serum after a single convulsive injection of pentylenetetrazol

Neuroscience Research

Volumn 43, Issue 3, 2002, Pages 283-288

  Bruno, Alessandra Nejar ^a   Oses, Jean Pierre ^a   Bonan, Carla Denise ^b   Walz, Roger ^c   Battastini, Ana Maria Oliveira ^a   Sarkis, João José Freitas ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

5 Nucleotidase; Adenosine; ATP diphosphohydrolase; Epilepsy; Nucleotidases; Seizures

Indexed keywords

4 NITROPHENYL 5' THYMIDINE MONOPHOSPHATE; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; LACTATE DEHYDROGENASE; NUCLEOTIDASE; PENTETRAZOLE; PHOSPHATE; PHOSPHODIESTERASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME SUBSTRATE; FEMALE; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; SEIZURE; ANIMAL; BLOOD; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; ENZYMOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; WISTAR RAT;

ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INJECTIONS, INTRAPERITONEAL; NUCLEOTIDASES; PENTYLENETETRAZOLE; RATS; RATS, WISTAR; SEIZURES; SUPPORT, NON-U.S. GOV'T; ANIMALS;

EID: 0036018106     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(02)00043-3     Document Type: Article

References (31)

1. Alterations of A1 adenosine receptors in different mouse brain areas after pentylenetetrazol-induced seizures, but not in epileptic mutant mouse ‘tottering’
2. Characterization of an ATP diphosphohydrolase (EC 3.6.1.5.) in synaptosomes from cerebral cortex of adult rats
3. Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats
4. Inhibitory avoidance learning inhibits ectonucleotidases activities in hippocampal synaptosomes of adult rats
5. Changes in synaptosomal ectonucleotidases activities in two rat models of temporal lobe epilepsy
6. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
7. 2+-ATPase activity
8. Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: Different roles, different sources and different receptors
9. Purinergic mechanisms in epilepsy
10. Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus
11. Adenosine: Potential mediator of seizure arrest and posticfal refractoriness
12. Adenosine: A molecule for synaptic homeostasis? Evolution of current concepts on the physiological and pathological roles of adenosine
13. Chronic hypoxia enhances adenosine release in rat PC12 cell by altering adenosine metabolism and membrane transport
14. Intracellular formation and release of adenosine from rat hippocampal slices evoked by electrical stimulation or energy depletion
15. Mechanism of action of epileptogenic drug pentylenetetrazol on a cloned neuronal potassium channel
16. Adenosine acts an endogeneous activator of the cellular antioxidant defense system
17. Effect of adenosine receptor modulation on pentylenetetrazole-induced seizures in rats
18. The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization
19. CD39-L4 is a secreted human Apyrase, specific for the hydrolysis of nucleoside diphosphates
20. The GABA postsynaptic membrane receptor-ionophore complex. Site of action convulsant and anticonvulsant drugs
21. Time development and regional distribution of [3H] nitrobenzylthioinosine adenosine uptake sites binding in the mouse brain after acute pentylenetetrazole-induced seizures
22. Effect of pentylentetrazol-induced seizures on A1 adenosine receptor regional density in the mouse brain: A quantitative autoradiographic study
23. Increase in plasma adenosine during brain ischemia in man: A study during transient ischemic attacks and stroke
24. The role of adenosine and its nucleotides in central synaptic transmission
25. Characterization of fetal serum 5′-nucleotide phosphodiesterase: A novel function as a platelet aggregation inhibitor in fetal circulation
26. Neuronal release of soluble nucleotidases and their role in neurotrasmitter inactivation
27. Kinetic analysis of enzymatic hydrolysis of ATP in human and rat blood serum
28. Effect of shear stress on the soluble ecto-enzymes ATPase and 5′-nucleotidase along with endogenous ATP from vascular endothelial cells
29. Brain adenosine production during the initial 60 s of bicuculline seizures in rats
30. Manipulation of endogenous adenosine in rat prepiform cortex modulates seizure susceptibility
31. Biochemistry, localization and functional role of ecto-nucleotidases in the nervous system