Functional retinoid and thyroid hormone receptors in human thyroid- carcinoma cell lines and tissues

International Journal of Cancer

Volumn 76, Issue 3, 1998, Pages 368-376

  Schmutzler, Cornelia ^a   Brtko, Julius ^b   Winzer, Ralf ^a   Jakobs, Tatjana C ^a   Meissner Weigl, Jutta ^a   Simon, Dietmar ^c   Goretzki, Peter E ^c   Köhrle, Josef ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b INSTITUTE OF EXPERIMENTAL ENDOCRINOLOGY   (Slovakia)

^c Klin F Allgemein Unfallchirurgie   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; MESSENGER RNA; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; THYROID HORMONE RECEPTOR;

ARTICLE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN DNA BINDING; RECEPTOR DENSITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THYROID CARCINOMA;

CARCINOMA; FEASIBILITY STUDIES; HUMANS; NEOPLASM PROTEINS; POLYMERASE CHAIN REACTION; RECEPTORS, RETINOIC ACID; RECEPTORS, THYROID HORMONE; RNA, MESSENGER; THYROID NEOPLASMS; TRETINOIN; TUMOR CELLS, CULTURED;

EID: 0031800394     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19980504)76:3<368::AID-IJC14>3.0.CO;2-7     Document Type: Article

References (22)

1. BARLOW, C., MEISTER, B., LARDELLI, M., LENDAHL, U. and VENNSTRÖM, B., Thyroid abnormalities and hepatocellular carcinoma in mice transgenic for v-erbA. EMBO J., 13, 4241-4250 (1994).
2. BRÖNNEGARD, M., TÖRRING, O., BÖÖS, J., SYLVEN, C., MARCUS, C. and WALLIN, G., Expression of thyrotropin-receptor and thyroid-hormone-receptor messenger ribonucleic acid in normal, hyperplastic and neoplastic human thyroid tissue. J. clin. Endocrinol. Metab., 79, 384-389 (1994).
3. BRTKO, J., Accurate determination and physicochemical properties of rat-liver nuclear-retinoic-acid (RA) receptors. Biochem. biophys. Res. Commun., 204, 439-445 (1994).
4. CHIRGWIN, J.M., PRZYBYLA, A.E., MACDONALD, R.J. and RUTTER, W.J., Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry, 18, 5294-5299 (1979).
5. DEL SENNO, L., ROSSI, R., FRANCESCHETTI, P. and DEGLI UBERTK E.C., Expression of all-trans-retinoic-acid-receptor RNA in human thyroid cells. Biochem. Mol. Biol. Int., 33, 1107-1115 (1994).
6. FARID, N.R., SHI, Y. and Zou, M., Molecular basis of thyroid cancer. Endocrine Rev., 15, 202-232 (1994).
7. HONG, W.K. and ITRI, L.M., Retinoids and human cancer. In: M.B. Sporn, A.B. Roberts and D.S. Goodman (eds.), The retinoids: biology, chemistry and medicine (2nd ed.). pp. 597-630, Raven Press, New York (1994).
8. JAKOBS, T.C., SCHMUTZLER, C., MEISSNER-WEIGL, J. and KÖHRLE, J., The promoter of the human type I 5′-deiodinase gene: mapping of the transcription start site and identification of a DR+4 thyroid-hormone-responsive element. Europ. J. Biochem., 247, 288-297 (1997).
9. LOVE, J.M. and GUDAS, L.J., Vitamin A, differentiation, and cancer. Curr. Opin. Cell Biol., 6, 825-831 (1994).
10. MANGELSDORFF, D.J. and EVANS, R.E., The RXR heterodimers and orphan receptors. Cell, 86, 841-850 (1995).
11. MANO, H., MORI, R., OZAWA, T., TAKEYAMA, K., YOSHIZAWA, Y., KOJIMA, R., ARAO, Y. MASUSHIGE, S. and KATO, S., Positive and negative regulation of retinoid-X-receptor-gene expression by thyroid hormone in the rat. Transcriptional and post-transcriptional controls by thyroid hormone. J. biol. Chem., 269, 1591-1594 (1994).
12. MIYOSHI, Y., NAKAMURA, H., TAGAMI, T., SASAKI, S. and NAKAO, K., 3,5,3′-triiodothyronine stimulates retinoic-acid-induced differentiation in HL-60 cells. Mol. cell. Endocrinol., 103, 119-123 (1994).
13. NILSSON, M., Actions of epidermal crowth factor in the thyroid. Trends Endocrinol. Metab., 6, 175-182 (1995).
14. PALLET, V. AUDOUIN-CHEVALLIER, I., VERRET, C., GARCIN, H. and HIGUERET, P., Retinoic acid differentially modulates triiodothyronine and retinoic-acid receptors in rat liver according to thyroid status. Europ. J. Endocrinol., 131, 377-384 (1994).
15. PFAHL, M. and CHYTIL, F., Regulation of metabolism by retinoic acid and its nuclear receptors. Ann. Rev. Nutr., 16, 257-283 (1996).
16. ROBERTSON, K.A., EMAMI, B. and COLLINS, S.J., Retinoic-acid-resistant HL-60R cells harbour a point mutation in the retinoic-acid-receptor ligand-binding domain that confers dominant negative activity. Blood, 80, 1885-1889 (1992).
17. SAKURAL A., NAKAI, A. and DE GROOT, L.J., Expression of three forms of thyroid-hormone receptor in human tissues. Mol. Endocrinol., 3, 392-399 (1989).
18. SCHMUTZLER, C., BRTKO, J., BIENERT, K. and KÖHRLE, Effects of retinoids and role of retinoic-acid receptors in human thyroid carcinomas and cell lines derived therefrom. Exp. clin. Endocrinol. Diab., 104 (Suppl. 4). 16-19 (1996).
19. SCHMUTZLER, C., WINZER, R., MEISSNER-WEIGL, J. and KÖHRLE, J., Retinoic acid increases sodium/iodide symporter mRNA levels in human thyroid-cancer cell lines and suppresses expression of functional symporter in non-transformed FRTL-5 rat thyroid cells. Biochem. biophys. Res. Commun., 240, 832-838 (1997).
20. SCHRECK, R., SCHNIEDERS, F., SCHMUTZLER, C. and KÖHRLE, J., Retinoids stimulate type-I iodothyronine 5′-deiodinase activity in human follicular thyroid-carcinoma cell lines. J. clin. Endocrinol. Metab., 79, 791-798 (1994).
21. SIMON, D., KÖHRLE, J., REINERS, C., BOERNER, A., SCHMUTZLER, C., MAINZ, K., GORETZKI, P.E. and RÖHER, H.D., Redifferentiation therapy with retinoids - a therapeutic option in advanced follicular and papillary thyroid carcinoma? Wld. J. Surg. (1998). (In press).
22. Xu, X.-C., SOZZI, G., LEE, J.S., LEE, J.J., PASTURING, U., PILOTTI, S., KURIE, J.M., HONG, W.K. and LOT AN, R., Suppression of retinoic-acid receptor β in non-small-cell lung cancer in vivo: implications for lung-cancer development. J. nat. Cancer Inst., 89, 624-629 (1997).