Hyper-reactivity of diacylglycerol kinase is involved in the dysfunction of aortic smooth muscle contractility in streptozotocin-induced diabetic rats

British Journal of Pharmacology

Volumn 136, Issue 3, 2002, Pages 441-451

  Nobe, Koji ^a   Sakai, Yasushi ^a   Maruyama, Yoshiaki ^a   Momose, Kazutaka ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

Calcium; Contraction; Insulin dependent diabetes mellitus; Norepinephrine; Phosphatidylinositol turnover; Protein kinase C; Vascular smooth muscle

Indexed keywords

DIACYLGLYCEROL KINASE; NORADRENALIN; PHOSPHATIDYLINOSITOL; POTASSIUM CHLORIDE; PROTEIN KINASE C; STREPTOZOCIN; ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM; INOSITOL; PHOSPHATIDIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA MEDIA; ARTICLE; CALCIUM CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; INSULIN DEPENDENT DIABETES MELLITUS; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTILITY; STREPTOZOCIN DIABETES; TURNOVER TIME; ANIMAL; AORTA; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; ENZYMOLOGY; EXPERIMENTAL DIABETES MELLITUS; IN VITRO STUDY; METABOLISM; MUSCLE CONTRACTION; VASCULAR SMOOTH MUSCLE; WISTAR RAT;

ANIMAL; AORTA; CALCIUM; DIABETES MELLITUS, EXPERIMENTAL; DIACYLGLYCEROL KINASE; IN VITRO; INOSITOL; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NOREPINEPHRINE; PHOSPHATIDIC ACIDS; POTASSIUM CHLORIDE; PROTEIN KINASE C; RATS; RATS, WISTAR; STREPTOZOCIN; SYMPATHOMIMETICS; ANIMALS;

EID: 0036016116     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704722     Document Type: Article

References (23)

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