Beneficial effects of caffeic acid phenethyl ester in a rat model of vascular injury

British Journal of Pharmacology

Volumn 136, Issue 3, 2002, Pages 353-360

  Maffia, Pasquale ^a   Ianaro, Angela ^b   Pisano, Barbara ^b   Borrelli, Francesca ^b   Capasso, Francesco ^b   Pinto, Aldo ^a   Ialenti, Armando ^b  

^a UNIVERSITY OF SALERNO   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Balloon angioplasty; CAPE; Cyclo oxygenase 2; Nuclear factor B; Restenosis; Vascular injury

Indexed keywords

BETA ACTIN; CAFFEIC ACID PHENETHYL ESTER; CELL DNA; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROPOLIS; PROTEIN P50; SYNAPTOTAGMIN; ACTIN; CAFFEIC ACID DERIVATIVE; DRUG DERIVATIVE; ISOENZYME; PHENETHYL ALCOHOL; PROSTAGLANDIN SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; BLOOD VESSEL INJURY; CAROTID ARTERY; CELL LEVEL; CELL NUCLEUS; CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; MALE; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; RAT; RESTENOSIS; ANIMAL; BIOSYNTHESIS; CAROTID ARTERY INJURY; CHEMICAL PHENOMENA; DRUG ANTAGONISM; GEL MOBILITY SHIFT ASSAY; INTIMA; MACROPHAGE; PATHOLOGY; TRANSLUMINAL CORONARY ANGIOPLASTY; WISTAR RAT;

ACTINS; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ANIMAL; CAFFEIC ACIDS; CAROTID ARTERY INJURIES; DEPRESSION, CHEMICAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ISOENZYMES; MACROPHAGES; MALE; NF-KAPPA B; PHENYLETHYL ALCOHOL; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE; RATS; RATS, WISTAR; TUNICA INTIMA; ANIMALS; CYCLOOXYGENASE 2; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

EID: 0036016103     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704720     Document Type: Article

References (31)

1. Antisense oligonucleotides to the P65 subunit of NF-κB inhibit human vascular smooth muscle cell adherence and proliferation and prevent neointima formation in rat carotid arteries
2. Endothelial superoxide production in the isolated rat heart during early reperfusion after ischemia. A histochemical study
3. The inducible transcription activator NF-κB: Regulation by distinct protein subunits
4. Function and activation of NF-κB in the immune system
5. Inhibition of oxidative stress in HeLa cells by chemopreventive agents
6. Review of the biological properties and toxicity of bee propolis (propolis)
7. Nuclear factor-κB activity and arterial response to balloon injury
8. Apoptosis and altered redox state induced by caffeic acid phenethyl ester (CAPE) in transformed rat fibroblast cells
9. A dilemma for the 1990s: Choosing appropriate experimental animal model for the prevention of restenosis
10. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
11. Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis
12. Role of nuclear factor-κB in a rat model of vascular injury
13. Smooth muscle cell proliferation is proportional to the degree of balloon injury in a rat model of angioplasty
14. The role of platelets, thrombin and hyperplasia in restenosis after coronary angioplasty
15. Evidence that inducible nitric oxide synthase is involved in LPS-induced plasma leakage in rat skin through the activation of nuclear factor-κB
16. Activation of the NF-κB and IκB system in smooth muscle cells after rat arterial injury: Induction of vascular cell adhesion molecule-1 and monocyte chemoattractant protein-1
17. Two related phenolic antioxidants with opposite effects on vitamin E content in low density lipoproteins oxidized by ferrylmyoglobin: Consumption vs regeneration
18. Apoptosis and cell proliferation after porcine coronary angioplasty
19. Inhibitory effect of caffeic acid phenethyl ester on the activity and expression of cyclo-oxygenase-2 in human oral epithelial cells and in a rat model of inflammation
20. The effect of propolis and its components on eicosanoids production during the inflammatory response
21. Reactive oxygen species and iron - A dangerous partnership in inflammation
22. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB
23. Evidence for involvement of COX-2 gene expression by IL-1β
24. Caffeic acid phenetyl ester induces leukocyte apoptosis, modulates nuclear factor kappaB and suppresses acute inflammation
25. The pathogenesis of atherosclerosis: A perspective for the 1990s
26. The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-κB
27. The intima: Soil for atherosclerosis and restenosis
28. Table? Growth suppression and toxicity induced by caffeic acid phenethyl ester (CAPE) in type 5 adenovirus-transformed rat embryo cells correlate directly with transformation progression
29. NF-κB: A lesson in family values
30. Frontiers in interventional cardiology
31. NF-κB and AP-1 activation by nitric oxide attenuated apoptotic cell death in RAW 264.7 macrophages