IL-1β expression in islet cells of the NOD mouse and its spatial relationship to beta cells and inducible nitric oxide synthase

Annals of the New York Academy of Sciences

Volumn 958, Issue , 2002, Pages 190-193

  Reddy, Shiva ^a   Young, May ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Beta cells; IL ; Islets; Macrophages; NOD mouse

Indexed keywords

CYCLOPHOSPHAMIDE; CYTOKINE; FREE RADICAL; INTERLEUKIN 1BETA; NICOTINAMIDE; NITRIC OXIDE SYNTHASE; INTERLEUKIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; CELL DEATH; CELLULAR DISTRIBUTION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; IMMUNOHISTOCHEMISTRY; INSULIN DEPENDENT DIABETES MELLITUS; MACROPHAGE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; SOMATOSTATIN CELL; ANIMAL; ARTICLE; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; ENZYME INDUCTION; ENZYMOLOGY; GENE EXPRESSION; IMMUNOLOGY; METABOLISM; NONOBESE DIABETIC MOUSE; PANCREAS ISLET; TIME;

ANIMALIA;

ANIMALS; CYCLOPHOSPHAMIDE; DIABETES MELLITUS, TYPE 1; ENZYME INDUCTION; FEMALE; GENE EXPRESSION; INTERLEUKIN-1; ISLETS OF LANGERHANS; MACROPHAGES; MICE; MICE, INBRED NOD; NIACINAMIDE; NITRIC OXIDE SYNTHASE; TIME FACTORS;

EID: 0036015652     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb02967.x     Document Type: Conference Paper

References (7)

1. Type 1 diabetes mellitus: A chronic autoimmune disease
2. The role of interleukin-1 in the pathogenesis of IDDM
3. An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus
4. An immunohistochemical study of macrophage influx and the co-localization of inducible nitric oxide synthase in the pancreas of nonobese (NOD) mice during disease acceleration with cyclophosphamide
5. Dual-label immunohistochemical study of interleukin-4- and interferon-γ-expressing cells within the pancreas of the NOD mouse during disease acceleration with cyclophosphamide
6. Interleukin-1β-induced nitric oxide synthase expression by rat pancreatic β-cells: Evidence for the involvement of nuclear factor κB in the signalling mechanism
7. Inducible nitric oxide synthase in pancreatic islets of the nonobese diabetic mouse: Light and confocal microscopical study of its ontogeny, colocalization and up-regulation following cytokine administration