MRG-1, a mortality factor-related chromodomain protein, is required maternally for primordial germ cells to initiate mitotic proliferation in C. elegans

Mechanisms of Development

Volumn 114, Issue 1-2, 2002, Pages 61-69

  Fujita, Masaki ^a   Takasaki, Teruaki ^a   Nakajima, Noboru ^b   Kawano, Taizo ^a   Shimura, Yoshiro ^b   Sakamoto, Hiroshi ^a  

^a KOBE UNIVERSITY   (Japan)

^b BIOMOL ENG RESEARCH INSTITUTE   (Japan)

Author keywords

Caenorhabditis elegans; Chromodomain; Germline; Primordial germ cell; RNA interference

Indexed keywords

PROTEIN; PROTEIN MRG 1; PROTEIN MRG 15; PROTEIN PGL 1; RNA; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; CITED2 PROTEIN, HUMAN; COMPLEMENTARY DNA; DNA BINDING PROTEIN; DOUBLE STRANDED RNA; HYBRID PROTEIN; MORF4L1 PROTEIN, HUMAN; MRG 1 PROTEIN, C ELEGANS; MRG-1 PROTEIN, C ELEGANS; REPRESSOR PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; CELL DEGENERATION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO DEVELOPMENT; FEMALE; GERM LINE; HERMAPHRODITISM; IMMUNOBLOTTING; MALE; MITOSIS; NONHUMAN; OOCYTE; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; WILD TYPE; ZYGOTE; AMINO ACID SEQUENCE; ANIMAL; CELL DIVISION; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; PHENOTYPE; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRENATAL DEVELOPMENT; WESTERN BLOTTING;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL DIVISION; CLONING, MOLECULAR; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOBLOTTING; MALE; MITOSIS; MOLECULAR SEQUENCE DATA; OOCYTES; PHENOTYPE; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; RNA; RNA, DOUBLE-STRANDED; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 0036011242     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(02)00058-8     Document Type: Article

References (48)

1. Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila
2. Chromodomains are protein-RNA interaction modules
3. Gain-of-function mutations of fem-3, a sex-determination gene in Caenorhabditis elegans
4. Transcriptional repression by the Caenorhabditis elegans germ-line protein PIE-1
5. Characterization of a germ-line proliferation mutation in C. elegans
6. Laser killing of cells in Caenorhabditis elegans
7. MES-1, a protein required for unequal divisions of the germline in early C. elegans embryos, resembles receptor tyrosine kinases and is localized to the boundary between the germline and gut cells
8. Conservation of the MORF4 related gene family: Identification of a new chromo domain subfamily and novel protein motif
9. Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes
10. The genetics of Caenorhabditis elegans
11. Identification of grandchildless loci whose products are required for normal germ-line development in the nematode Caenorhabditis elegans
12. The yeast NuA4 and Drosophila MSL complexes contain homologous subunits important for transcriptional regulation
13. Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster
14. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
15. The phenotype of mes-2, mes-3, mes-4 and mes-6, maternal-effect genes required for survival of the germline in Caenorhabditis elegans, is sensitive to chromosome dosage
16. Molecular characterization of the male-specific lethal-3 gene and investigations of the regulation of dosage compensation in Drosophila
17. The mog-1 gene is required for the switch from spermatogenesis to oogenesis in Caenorhabditis elegans
18. Genetics of cell and axon migrations in Caenorhabditis elegans
19. Lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans
20. C. elegans POP-1/TCF functions in a canonical Wnt pathway that controls cell migration and in a noncanonical Wnt pathway that controls cell polarity
21. Segregation of germ granules in living Caenorhabditis elegans embryos: Cell-type-specific mechanisms for cytoplasmic localization
22. Nondisjunction mutants of the nematode Caenorhabditis elegans
23. Sex determination in the nematode C. elegans: Analysis of tra-3 suppressors and characterization of fem genes
24. MES-2, a maternal protein essential for viability of the germline in Caenorhabditis elegans, is homologous to a Drosophila Polycomb group protein
25. The Caenorhabditis elegans gonad: A test tube for cell and developmental biology
26. PGL-1, a predicted RNA-binding component of germ granules, is essential for fertility in C. elegans
27. Fertlization and establishment of polarity in the embryo
28. Identification of genes required for cytoplasmic localization in early C. elegans embryos
29. On the control of germ cell development in Caenorhabditis elegans
30. The Polycomb group in Caenorhabditis elegans and maternal control of germline development
31. The chromo superfamily: New members, duplication of the chromo domain and possible role in delivering transcription regulators to chromatin
32. Origin and evolution of the regulatory gene male-specific lethal-3
33. The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos
34. The PIE-1 protein and germline specification in C. elegans embryos
35. A chromodomain protein, Swi6, performs imprinting functions in fission yeast during mitosis and meiosis
36. Phenotypic and molecular analysis of mes-3, a maternal-effect gene required for proliferation and viability of the germ line in C. elegans
37. Components of the SWI/SNF complex are required for asymmetric cell division in C. elegans
38. Launching the germline in Caenorhabditis elegans: Regulation of gene expression in early germ cells
39. The Drosophila MSL complex acetylates histone H4 at lysine 16, a chromatin modification linked to dosage compensation
40. Immunofluorescence visualization of germ-line-specific cytoplasmic granules in embryos, larvae, and adults of Caenorhabditis elegans
41. Transformation of the germ line into muscle in mes-1 mutant embryos of C. elegans
42. The embryonic cell lineage of the nematode Caenorhabditis elegans
43. Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision
44. Characterization of the CHD family of proteins
45. Germ cells
46. Heterochromatin protein 1 binds to nucleosomes and DNA in vitro