GPIIb/IIIa is the main receptor for initial platelet adhesion to glass and titanium surfaces in contact with whole blood

Journal of Laboratory and Clinical Medicine

Volumn 139, Issue 3, 2002, Pages 163-172

  Broberg, Marita ^a   Eriksson, Cecilia ^a   Nygren, Håkan ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; COLLAGEN; FIBRINOGEN; FIBRINOGEN RECEPTOR; GLASS; MONOCLONAL ANTIBODY; TITANIUM;

ANIMAL; ARTICLE; BLOOD; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; IMMUNOBLOTTING; IMMUNOLOGY; METABOLISM; MOUSE; PHYSICAL CHEMISTRY; PHYSIOLOGY; SURFACE PROPERTY; THROMBOCYTE; THROMBOCYTE ADHESIVENESS;

ADENOSINE DIPHOSPHATE; ANIMALS; ANTIBODIES, MONOCLONAL; BLOOD; BLOOD PLATELETS; CHEMISTRY, PHYSICAL; COLLAGEN; FIBRINOGEN; FLUORESCENT ANTIBODY TECHNIQUE; GLASS; HUMANS; IMMUNOBLOTTING; MICE; PLATELET ADHESIVENESS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; SURFACE PROPERTIES; TITANIUM;

EID: 0036010035     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1067/mlc.2002.121604     Document Type: Article

References (58)

1. The initial reactions of graphite and gold with blood
2. Platelet interactions with surface-adsorbed plasma proteins: Exposure of CD62P induced by von Willebrand factor
3. The effect of adsorbed fibrinogen, fibronectin, von Willebrand factor and vitronectin on the procoagulant state of adherent platelets
4. Polymorphonuclear leukocytes in coagulating whole blood recognize hydrophilic and hydrophobic titanium surfaces by different adhesion receptors and show different patterns of receptor expression
5. The response of bone to titanium implants
6. Bone response to surface modified titanium implants: Studies on electropolished implants with different oxide thicknesses and morphology
7. Bone response to surface-modified titanium implants: Studies on the early tissue response to machined and electropolished implants with different oxide thicknesses
8. Adsorption of coagulation proteins and adhesion and activation of platelets at the blood-solid interface: An experimental study of human whole blood
9. Interaction of high molecular weight kininogen, factor XII, and fibrinogen in plasma at interfaces
10. The effect of plasma proteins on the interaction of platelets with glass surfaces
11. Platelet adhesion induced by fibrinogen adsorbed onto glass
12. Effect of fibrinogen concentration on platelet adhesion to glass
13. Von Willebrand factor in the vessel wall mediates platelet adherence
14. Antibodies to CD36 (GPIV) inhibit platelet adhesion to subendothelial surfaces under flow conditions
15. Identification of two structurally and functionally distinct sites on human platelet membrane glycoprotein IIb-IIIa using monoclonal antibodies
16. The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis
17. Calcium cation regulation of glycoprotein IIb-IIIa complex formation in platelet plasma membranes
18. Adhesive properties of the beta 3 integrins: Comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cells
19. The ligand binding site of the platelet integrin receptor GPIIb-IIIa is proximal to the second calcium binding domain of its alpha subunit
20. Selective recognition of adhesive sites in surface-bound fibrinogen by glycoprotein IIb-IIIa on nonactivated platelets
21. Co-localization of CD9 and GPIIb-IIIa (alpha IIb beta 3 integrin) on activated platelet pseudopods and alpha-granule membranes
22. The platelet antigens CD9, CD42 and integrin alpha IIb beta IIIa can be topographically associated and transduce functionally similar signals
23. Topographical association of the platelet Fc-receptor with the glycoprotein IIb-IIIa complex
24. Fc gamma II receptor-mediated platelet activation induced by anti-CD9 monoclonal antibody opens Ca2+ channels which are distinct from those associated with Ca2+ store depletion
25. Interaction of purified actin-binding protein with the platelet membrane glycoprotein Ib-IX complex
26. The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress
27. Platelet GPIb-V-IX complex
28. Phagocytosis and hydrophobicity: A method of calculating contact angles based on the diameter of sessile drops
29. Initial reactions of whole blood with hydrophilic and hydrophobic titanium surfaces
30. Specific activation of platelets by surface-adsorbed plasma proteins
31. A method for purifying the platelet membrane glycoprotein IIb-IIIa complex
32. Characterization of melanoma-associated surface antigens involved in the adhesion and motility of human melanoma cells
33. Platelet adhesion to fibronectin in flow: Dependence on surface concentration and shear rate, role of platelet membrane glycoproteins GP IIb/IIIa and VLA-5, and inhibition by heparin
34. A monoclonal antibody to the human platelet glycoprotein IIb/IIIa complex induces platelet activation
35. Anti-GPIIb/IIIa (CD41) monoclonal antibody-induced platelet activation requires Fc receptor-dependent cell-cell interaction
36. Interaction of two GPIIb/IIIa monoclonal antibodies with platelet Fc receptor (Fc gamma RII)
37. Activation of human platelets by exposure to a monoclonal antibody, PM6/248, to glycoprotein IIb-IIIa
38. Studies on the dual effects on platelets of a monoclonal antibody to CD9, and on the properties of platelet CD9
39. Glycoprotein Ib-V-IX, a receptor for von Willebrand factor, couples physically and functionally to the Fc receptor gamma-chain, Fyn, and Lyn to activate human platelets
40. Does the conformation of adsorbed fibrinogen dictate platelet interactions with artificial surfaces?
41. Baboon fibrinogen adsorption and platelet adhesion to polymeric materials
42. Human plasma fibrinogen adsorption and platelet adhesion to polystyrene
43. Integrin receptors and platelet adhesion to synthetic surfaces
44. Characterization of the fibrinogen binding sites using monoclonal antibodies to human platelet membrane glycoprotein IIb/IIIa
45. Platelet integrins
46. Monoclonal antibodies against human platelet glycoprotein IIIa
47. A monoclonal antibody binding to human medulloblastoma cells and to the platelet glycoprotein IIB-IIIA complex
48. Integrin alpha IIb beta 3-mediated pp125FAK phosphorylation and platelet spreading on fibrinogen are regulated by PI 3-kinase
49. Pathophysiology of platelet thrombin receptors
50. Characterization of the IgG-Fc receptor on human platelets
51. Characterization of a platelet membrane protein of low molecular weight associated with platelet activation following binding by monoclonal antibody AG-1
52. Isolation and characterization of a platelet membrane protein related to the vitronectin receptor
53. Alpha-granule pool of glycoprotein IIb-IIIa in normal and pathologic platelets and megakaryocytes
54. Platelet dense granules: Structure, function and implications for haemostasis
55. Effects of sodium azide on platelet function
56. The sulfhydryl reagent thimerosal elicits human platelet aggregation by mobilization of intracellular calcium and secondary prostaglandin endoperoxide formation
57. Kinetics of merthiolate-induced aggregation of human platelets
58. Platelet adhesion and procoagulant activity induced by contact with radiofrequency glow discharge polymers: Roles of adsorbed fibrinogen and vWF