Eicosanoids in sickle cell disease: Potential relevance of neutrophil leukotriene B4 to disease pathophysiology

Journal of Laboratory and Clinical Medicine

Volumn 139, Issue 2, 2002, Pages 80-89

  Setty, B N Yamaja ^a   Stuart, Marie J ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; HEMOGLOBIN F; L SELECTIN; LEUKOTRIENE B4; MESSENGER RNA; VITRONECTIN RECEPTOR;

ADOLESCENT; ADULT; ARTICLE; BLOOD; CELL ADHESION; CHEMISTRY; CHILD; ERYTHROCYTE; GENE EXPRESSION; GENETICS; GENOTYPE; HUMAN; LEUKOCYTE COUNT; METABOLISM; NEUTROPHIL; PAIN; PATHOLOGY; PHYSIOLOGY; PRESCHOOL CHILD; REFERENCE VALUE; RETICULOCYTE COUNT; SICKLE CELL ANEMIA; SYNDROME; THORAX PAIN; URINE; VASCULAR DISEASE; VASCULAR ENDOTHELIUM;

ADOLESCENT; ADULT; ANEMIA, SICKLE CELL; CELL ADHESION; CHEST PAIN; CHILD; CHILD, PRESCHOOL; ENDOTHELIUM, VASCULAR; ERYTHROCYTES; FETAL HEMOGLOBIN; GENE EXPRESSION; GENOTYPE; HEMOGLOBINS; HUMANS; L-SELECTIN; LEUKOCYTE COUNT; LEUKOTRIENE B4; NEUTROPHILS; PAIN; RECEPTORS, VITRONECTIN; REFERENCE VALUES; RETICULOCYTE COUNT; RNA, MESSENGER; SYNDROME; VASCULAR DISEASES;

EID: 0036009342     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1067/mlc.2002.121200     Document Type: Article

References (41)

1. Pathogenesis and treatment of sickle cell disease
2. Adhesive interactions of sickle erythrocytes with endothelium
3. Anti-adhesion therapy in sickle cell disease
4. Management of sickle cell disease
5. Adhesion of sickle neutrophils and erythrocytes to fibronectin
6. Sickle erythrocytes adhere to polymorphonuclear neutrophils and activate the neutrophil respiratory burst
7. Blood polymorphonuclear leucocytes from the majority of SCD patients in the crisis phase of the disease show enhanced adhesion to vascular endothelium and increased expression of CD64
8. 2 activity and defective priming of NADPH oxidase and phospholipase A2 in sickle cell disease
9. Neutrophil activation in sickle cell disease
10. Leukotrienes and lipoxine: Structures, biosynthesis and biological effects
11. Sickle cell vaso-occlusive crisis is associated with abnormalities in the ratio of vasoconstrictor to vasodilator prostanoids
12. Arachidonic acid metabolites are involved in mediating red blood cell adhesion to endothelium
13. Eicosanoids in sickle cell disease: Potential relevance of 12(s)-hydroxy-5,8,10,14-eicosatetraenoic acid to the pathophysiology of vaso-occlusion
14. 4 in inflammation
15. 4, but not formylmethionyl leucylphenylalanine, stimulate CD18-independent migration of neutrophils across human pulmonary endothelial cells in vitro
16. 4 induced hyperadhesiveness of endothelial cells for neutrophils
17. Identification of prostaglandins and hydroxyeicosatetraenoic acids in kitten retina: Comparison with other species
18. Isolation and culture of cells from human retinal microvessels
19. Erythrocyte adherence to endothelium in sickle-cell anemia: A possible determinant of disease severity
20. 3 Integrin expression in normal and atherosclerotic artery
21. Modulation of ICAM-1 expression in human alveolar macrophages in vitro
22. Hypoxia-reoxygenation causes inflammatory response in transgenic sickle mice but not in normal mice
23. Sickle cell anemia as an inflammatory disease
24. Leucocyte counts in children with sickle cell disease: Comparative values in the steady state, vaso-occlusive crisis and bacterial infections
25. Laboratory profiles of SCD: A cross-sectional analysis. The cooperative study of sickle cell disease
26. Mortality in sickle cell disease: Life expectancy and risk factors for early death
27. Prediction of adverse outcomes in children with sickle cell disease
28. The acute chest syndrome in sickle cell disease: Incidence and risk factors. The cooperative study of sickle cell disease
29. Silent cerebral infarcts in sickle cell anemia: A risk factor analysis. The cooperative study of sickle cell disease
30. Neutrophil CD64 expression: Potential diagnostic indicator of acute inflammation and therapeutic monitor of interferon-γ therapy
31. Membrane proximal cleavage of L-selectin: Identification of the cleavage site and a 6-KD transmembrane peptide fragment of L-selectin
32. 4 levels in the arterial blood of asthmatic patients and the effects of prednisolone
33. Elevated plasma level of leukotrienes in bronchial asthma patients: A possible clinical relevance
34. 4 in human plasma by negative ion chemical ionization/gas chromatography/tandem mass spectrometry
35. Plasma and urinary leukotrienes in sickle cell disease: Possible role in the inflammatory process
36. Measurement of eicosanoids by bioassay and radioimmunoassay
37. 100 fact or fiction?
38. Reexamination of the assay for plasma prostanoids by solid-phase extraction, and radioimmunoassay
39. Platelet regulatory prostanoids and release products in sickle cell disease
40. 2 agonist U46619
41. Elevated urinary levels of thromboxane and prostacyclin metabolites in sickle cell disease reflects activated platelets in the circulation