Application of fetal DNA in maternal plasma for noninvasive prenatal diagnosis

Expert Review of Molecular Diagnostics

Volumn 2, Issue 1, 2002, Pages 32-40

  Chiu, Rossa W K ^a   Lo, Y M Dennis ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Diagnosis; Noninvasive; Plasma DNA; Prenatal; Quantitative PCR; Real time

Indexed keywords

NUCLEIC ACID; RHESUS D ANTIGEN; DNA;

AUTOSOMAL DOMINANT DISORDER; DIAGNOSTIC PROCEDURE; DNA DETERMINATION; FEMALE; FETUS; GENE DELETION; GENE SEQUENCE; GENETIC DISORDER; GENOTYPE; HUMAN; MALE; MATERNAL PLASMA; NON INVASIVE MEASUREMENT; PREECLAMPSIA; PRENATAL DIAGNOSIS; QUANTITATIVE ASSAY; REVIEW; Y CHROMOSOME; BLOOD; FETOMATERNAL TRANSFUSION; METHODOLOGY; PREGNANCY;

DNA; FEMALE; FETUS; GENETIC DISEASES, INBORN; GENOTYPE; HUMANS; MALE; MATERNAL-FETAL EXCHANGE; PREGNANCY; PRENATAL DIAGNOSIS;

EID: 0035998301     PISSN: 14737140     EISSN: None     Source Type: Journal    
DOI: 10.1586/14737159.2.1.32     Document Type: Review

References (53)

1. Presence of fetal DNA in maternal plasma and serum
2. Les acides nudeiques du plasma sanguin chez l'Homme
3. Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus
4. Free DNA in the serum of cancer patients and the effect of therapy
5. Microsatellite alterations in plasma DNA of small cell lung cancer patients
6. Microsatellite alterations in serum DNA of head and neck cancer patients
7. Quantitative analysis of fetal DNA in maternal plasma and serum: Implications for noninvasive prenatal diagnosis
8. Fetal cells in the maternal circulation: Feasibility for prenatal diagnosis
9. Fetal cells in maternal blood: NIFTY clinical trial interim analysis. DM-STAT
10. PCR quantitation of fetal cells in maternal blood in normal and aneuploid pregnancies
11. Quantification of all fetal nucleated cells in maternal blood between the 18th-22nd weeks of pregnancy using molecular cytogenetic techniques
12. Fetal DNA in maternal plasma is elevated in pregnancies with aneuploid fetuses
13. Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum
14. Accuracy of fetal gender determination by analysis of DNA in maternal plasma
15. Fetal gender determination in early pregnancy through qualitative and quantitative analysis of fetal DNA in maternal serum
16. Detection and quantification by homogeneous PCR of cell-free fetal DNA in maternal plasma
17. Randomised study of risk of fetal loss related to early amniocentesis versus chorionic villus sampling
18. Rapid clearance of fetal DNA from maternal plasma
19. Successful diagnosis of fetal gender using conventional PCR analysis of maternal serum
20. Prenatal identification of fetal genetic traits
21. Fetal sex determination from maternal plasma in pregnancies at risk for congenital adrenal hyperplasia
22. Detection of fetal RHD-specific sequences in maternal plasma
23. Prenatal diagnosis of fetal RhD status by molecular analysis of maternal plasma
24. Prediagnosis evaluation of fetal RHD PCR-typing using DNA from maternal plasma
25. Prenatal determination of fetal blood group status
26. Noninvasive fetal RHD genotyping using maternal plasma
27. Risk free simultaneous prenatal identification of fetal Rhesus D status and sex by multiplex real-time PCR using cell free fetal DNA in maternal plasma
28. Evidence of genetic diversity underlying Rh D-, weak D (Du), and partial D phenotypes as determined by multiplex polymerase chain reaction analysis of the RHD gene
29. The RHD gene is highly detectable in RhD-negative Japanese donors
30. Prenatal diagnosis of myotonic dystrophy using fetal DNA obtained from maternal plasma
31. Prenatal DNA diagnosis of a single-gene disorder from maternal plasma
32. Fetal DNA in maternal plasma: The prenatal detection of a paternally inherited fetal aneuploidy
33. Fetal DNA analyzed in plasma from a mother's three consecutive pregnancies to detect paternally inherited aneuploidy
34. Detection of fetal-derived paternally inherited X-chromosome polymorphisms in maternal plasma
35. Detection of male and female fetal DNA in maternal plasma by multiplex fluorescent polymerase chain reaction amplification of short tandem repeats
36. Quantitative abnormalities of fetal DNA in maternal serum in preedampsia
37. Elevation of both maternal and fetal extracellular circulating deoxyribonucleic acid concentrations in the plasma of pregnant women with preedampsia
38. Increased maternal plasma fetal DNA concentrations in women who eventually develop preedampsia
39. Increased fetal DNA concentrations in the plasma of pregnant women carrying fetuses with trisomy 21
40. Quantitation of fetal DNA in maternal serum in normal and aneuploid prenancies
41. Maternal plasma fetal DNA as a marker for preterm labour
42. Cell-free fetal deoxyribonudeic acid in maternal circulation as a marker of fetal-maternal hemorrhage in patients undergoing external cephalic version near term
43. Detection of apoptotic fetal cells in plasma of pregnant women
44. Prenatal detection of fetal Down's syndrome from maternal plasma
45. Noninvasive prenatal diagnosis of congenital adrenal hyperplasia through the use of fetal DNA in maternal plasma
46. Differential DNA methylation between fetus and mother as a strategy for detecting fetal DNA in matemal plasma
47. Effects of blood-processing protocols on fetal and total DNA quantification in maternal plasma
48. Large amounts of cell-free fetal DNA are present in amniotic fluid
49. Fetal DNA in maternal plasma: Emerging clinical applications
50. Presence of fetal RNA in maternal plasma
51. Two-way cell traffic between mother and fetus: Biologic and clinical implications
52. Quantitative analysis of the bidirectional fetomaternal transfer of nucleated cells and plasma DNA
53. Apoptosis in fetal nucleated erythrocytes circulating in maternal blood