3-Deazaneplanocin A induces massively increased interferon-α production in Ebola virus-infected mice

Antiviral Research

Volumn 55, Issue 1, 2002, Pages 151-159

  Bray, Mike ^a   Raymond, Jo Lynne ^a   Geisbert, Tom ^a   Baker, Robert O ^a  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

Antiviral therapy; Ebola virus; Filovirus; Interferon alpha; S Adenosyl L homocysteine hydrolase

Indexed keywords

3 DEAZANEPLANOCIN A; ADENOSYLHOMOCYSTEINASE; ALPHA INTERFERON; CELL ENZYME; MESSENGER RNA; 3 DEAZANEPLANOCIN; 3-DEAZANEPLANOCIN; ADENOSINE; DRUG DERIVATIVE;

5' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA VIRUS; DRUG EFFECT; DRUG EFFICACY; EBOLA VIRUS; ENZYME INHIBITION; FEMALE; METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RNA VIRUS; TREATMENT OUTCOME; VIREMIA; VIRUS INFECTION; VIRUS REPLICATION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; BLOOD; COMPARATIVE STUDY; DISEASE MODEL; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; LIVER; PATHOLOGY; VIROLOGY; VIRUS HEMORRHAGIC FEVER;

ADENOSINE; ANIMAL; COMPARATIVE STUDY; DISEASE MODELS, ANIMAL; EBOLA-LIKE VIRUSES; FEMALE; HEMORRHAGIC FEVER, EBOLA; IMMUNOHISTOCHEMISTRY; INTERFERON-ALPHA; LIVER; MICE; MICE, INBRED BALB C; VIREMIA; ANIMALS; EBOLAVIRUS;

ANIMALIA; DNA VIRUSES; EBOLA VIRUS; MARBURG-LIKE VIRUSES; PRIMATES; RNA VIRUSES;

EID: 0035997942     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(02)00018-9     Document Type: Article

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