Effect of nizatidine on paracetamol and its metabolites in human plasma

Journal of Pharmacy and Pharmacology

Volumn 54, Issue 6, 2002, Pages 869-873

  Itoh, Hiroki ^a   Nagano, Toshiaki ^a   Takeyama, Masaharu ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALONAL; DRUG METABOLITE; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; HISTAMINE H2 RECEPTOR ANTAGONIST; NIZATIDINE; PARACETAMOL; PLACEBO; SULFATE; ACETAMINOPHEN SULFATE ESTER; ANALGESIC AGENT; DRUG DERIVATIVE; PARACETAMOL GLUCURONIDE;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG MEGADOSE; DRUG METABOLISM; DRUG POTENTIATION; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; LIVER METABOLISM; MALE; NORMAL HUMAN; STATISTICAL SIGNIFICANCE; VENOUS BLOOD; BLOOD; DRUG INTERACTION; ORAL DRUG ADMINISTRATION;

ACETAMINOPHEN; ADMINISTRATION, ORAL; ADULT; ANALGESICS, NON-NARCOTIC; AREA UNDER CURVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HISTAMINE H2 ANTAGONISTS; HUMAN; MALE; NIZATIDINE; HUMANS;

EID: 0035997902     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357021779050     Document Type: Article

References (14)

1. Nizatidine disposition in subjects with normal and impaired renal function
2. 2-receptor antagonists
3. Simple and rapid assay for acetaminophen and conjugated metabolites in low-volume serum samples
4. Paracetamol and phenacetin
5. The effect of cimetidine and ranitidine on paracetamol glucuronidation and sulphation in cultured rat hepatocytes
6. Drug interaction between cyclosporin A and nizatidine in Sprague-Dawley rats
7. The dependence of paracetamol absorption on the rate of gastric emptying
8. Ranitidine raises bioavailability of acetaminophen by inhibiting the first-pass glucuronidation in man
9. Nizatidine, an H2-blocker. Its metabolism and disposition in man
10. 2-receptor antagonist, on gastric acid secretion in dogs, rats and frogs
11. Determination of phenacetin and its major metabolites in human plasma and urine by high-performance liquid chromatography
12. Nizatidine. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in peptic ulcer disease
13. Drug absorption, metabolism, and excretion. I. Some pharmacokinetic aspects of metabolism of acetanilide 4-hydroxyacetanilide
14. 2-receptor antagonist, and its possible mechanism of action in dogs and rats