Ranitidine increases bioavailability of acetaminophen by inhibiting first-pass glucuronidation in man

Pharmacy and Pharmacology Communications

Volumn 6, Issue 11, 2000, Pages 495-500

  Itoh, H ^a   Nagano, T ^a   Hayashi, T ^a   Takeyama, M ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALONAL; PARACETAMOL; PARACETAMOL GLUCURONIDE; PARACETAMOL SULFATE; PLACEBO; RANITIDINE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG GLUCURONIDATION; DRUG METABOLISM; FIRST PASS EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; LIVER METABOLISM; MALE; NORMAL HUMAN; TABLET;

EID: 0033645966     PISSN: 14608081     EISSN: None     Source Type: Journal    
DOI: 10.1211/146080800128735584     Document Type: Article

References (13)

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13. 2-receptor antagonist, and its possible mechanism of action in dogs and rats