Host focal adhesion protein domains that bind to the translocated intimin receptor (Tir) of enteropathogenic Escherichia coli (EPEC)

Cell Motility and the Cytoskeleton

Volumn 52, Issue 4, 2002, Pages 255-265

  Huang, Lily ^a   Mittal, Balraj ^a,b   Sanger, Joseph W ^a   Sanger, Jean M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Alpha actinin; Pathogens; Pedestals; Talin; Vinculin

Indexed keywords

ALPHA ACTININ; INTIMIN; TALIN; VINCULIN; ACTININ; CELL SURFACE RECEPTOR; ESCHERICHIA COLI PROTEIN; HYBRID PROTEIN; TIR PROTEIN, E COLI;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONTROLLED STUDY; DIARRHEA; ESCHERICHIA COLI; FOCAL ADHESION; HOST CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; RECEPTOR BINDING; ANIMAL; BINDING SITE; CELL LINE; GENETICS; HUMAN; METABOLISM; PATHOGENICITY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; TWO HYBRID SYSTEM;

ACTININ; ANIMAL; BINDING SITES; CELL LINE; CELL MEMBRANE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HUMAN; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; RECOMBINANT FUSION PROTEINS; SUPPORT, U.S. GOV'T, NON-P.H.S.; TALIN; TWO-HYBRID SYSTEM TECHNIQUES; VINCULIN; ANIMALS; HUMANS;

ANIMALIA; ESCHERICHIA COLI;

EID: 0035997135     PISSN: 08861544     EISSN: None     Source Type: Journal    
DOI: 10.1002/cm.10050     Document Type: Article

References (33)

1. Talin, a host cell protein, interacts directly with the translocated intimin receptor, Tir, of enteropathogenic Escherichia coli, and is essential for pedestal formation
2. Enteropathogenic Escherichia coli (EPEC) attachment to epithelial cells: Exploiting the host cell cytoskeleton from the outside
3. Focal adhesions: The cytoskeletal connection
4. Identification of the intimin-binding domain of Tir of enteropathogenic Escherichia coli
5. Enterohemorrhagic Escherichia coli O157:1-17 produces Tir, which is translocated to the host cell membrane but is not tyrosine phosphorylated
6. Enterohaemorrhagic and enteropathogenic Escherichia coli use a different Tir-based mechanism for pedestal formation
7. Intact alpha-actinin molecules are needed for both the assembly of actin into the tails and the locomotion of Listeria monocytogenes inside infected cells
8. Role of the eaeA gene in experimental enteropathogenic Escherichia coli infection
9. Interaction of the enteropathogenic Escherichia coli protein, translocated intimin receptor (Tir), with focal adhesion proteins
10. Natural infection with attaching and effacing Escherichia coli (O 103:H-) in chicks
11. Recruitment of cytoskeletal and signaling proteins to enteropathogenic and enterohemorrhagic Escherichia coli pedestals
12. Enteropathogenic E. coli translocated in-timin receptor, Tir, interacts directly with alpha-actinin
13. Gut feelings: Enteropathogenic E. coli (EPEC) interactions with the host
14. Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells
15. Innate mechanisms of epithelial host defense: Spotlight on intestine
16. Talin dynamics in living microinjected nonmuscle cells
17. Host-microbial symbiosis in the mammalian intestine: Exploring an internal ecosystem
18. Escherichia coli that cause diarrhea: Enterotoxigenic, enteropathogenic, enteroinvasive, enterohemorrhagic and enteroadherent
19. Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex
20. Role of Tir and intimin in the virulence of rabbit enteropathogenic Escherichia coli serotype O103:H2
21. Diarrheagenic Escherichia coli
22. The gastrointestinal tract
23. IpgD, aprotein secreted by the type III secretion machinery of Shigella Flexneri, is chaperoned by IpgE and implicated in early focus formation
24. Characterization of the interaction partners of secreted proteins and chaperones of Shigella flexneri
25. Sequence and domain structure of talin
26. Novel form of actin-based motility transports bacteria on the surfaces of infected cells
27. Microinjection of fluorescently labeled alpha-actinin into living cells
28. Assembly of myofibrils in cardiac muscle cells
29. Microbial ecology of the gastrointestinal tract
30. A model to describe actin dynamics beneath EPEC and EHEC in infected cells
31. Exploitation of host cells by enteropathogenic Escherichia coli
32. Crystal structure of the alpha-actinin rod reveals an extensive torsional twist
33. Molecular structure of the sarcomeric Z-disk: Two types of titin interactions lead to an asymmetrical sorting of alpha-actinin