Metabolism of angiotensin I in the coronary circulation of normal and diabetic rats

Peptides

Volumn 23, Issue 6, 2002, Pages 1171-1175

  Mahmood, Asim ^a   Jackman, Herbert L ^b   Teplitz, Linda ^a   Igic, Rajko ^a,c  

^a Jr Hospital of Cook County   (United States)

^b UNIVERSITY OF ILLINOIS   (United States)

^c UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

Angiotensin 1 7; Angiotensin 1 9; Angiotensin I; Angiotensin II; Diabetes mellitus; Isolated perfused heart; Rat; Streptozotocin

Indexed keywords

ANGIOTENSIN DERIVATIVE; ANGIOTENSIN I; ANGIOTENSIN[1-7]; ANGIOTENSIN[1-9]; UNCLASSIFIED DRUG; ANGIOTENSIN I (1 7); ANGIOTENSIN I (1-7); PEPTIDE FRAGMENT;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY BLOOD VESSEL; HEART; HEART MUSCLE INJURY; HEART MUSCLE PERFUSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE DETERMINATION; HORMONE METABOLISM; ISOLATED ORGAN; MALE; METABOLITE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; PROTEIN METABOLISM; RAT; STREPTOZOCIN DIABETES; VASOCONSTRICTION; ANIMAL; BLOOD; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; PERFUSION; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANGIOTENSIN I; ANIMAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CORONARY CIRCULATION; DIABETES MELLITUS, EXPERIMENTAL; HEART; MALE; PEPTIDE FRAGMENTS; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; SUPPORT, NON-U.S. GOV'T; ANIMALS;

EID: 0035996859     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(02)00051-7     Document Type: Article

References (26)

1. Nephrectomy, converting enzyme inhibition, and angiotensin peptides
2. N-domain specific substrates and C-domain inhibitors of angiotensin-converting enzyme: Angiotensin-(1-7) and keto-ACE
3. Angiotensin II and the heart. On the intracrine renin-angiotensin system
4. Direct cardiac effects of angiotensins I and II and two converting enzyme inhibitors (captopril and perindopril). Indirect demonstration of a converting enzyme in the rat heart
5. Altered myocardial mechanics in diabetic rats
6. Angiotensin-(1-7) potentiates the hypotensive effect of bradykinin in conscious rats
7. Angiotensin-(1-7): A bioactive fragment of the renin-angiotesnin system
8. Angiotensin III: Evidence and speculation for its role as an important agonist in the renin-angiotesin system
9. Angiotensin IV has mixed effects on left ventricle systolic function and speed's relaxiation
10. A simple test for autonomic neuropathy in juvenile diabetics
11. The isolated perfused working rat heart: A new method
12. Metabolism of angiotensin I by guinea pig aqueous humor
13. Angiotensin I converting enzyme of the lung
14. Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system
15. A peptidase in human platelets that deamidates tachykinins. Probable identity with the lysosomal protective protein
16. The cardiac renin-angiotensin system. An appraisal of present experimental and clinical evidence
17. Experimental diabetes is associated with functional activation of protein kinase C epsilon and phosphorylation of troponin I in the heart, which are prevented by angiotensin II receptor blockade
18. Metabolism of angiotensin I in isolated rat hearts. Effect of angiotensin converting enzyme inhibitors
19. Effect of angiotensin-(1-7) on reperfusion arrhythmias in isolated rat hearts
20. Mortality in diabetic patients with cardiovascular autonomic neuropathy
21. Aminopeptidase A, which generates one of the main effector peptides of the brain renin-angiotensin system, angiotensin III, has a key role in central control of arterial blood pressure
22. The ACE-inhibitor captopril improves myocardial perfusion in spontaneously diabetic (BB) rats
23. 10-angiotensin I: A potential mechanism of endogenous angiotensin-converting enzyme regulation
24. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
25. Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells
26. Abnormal cardiac function in diabetic patients with autonomic neuropathy in the absence of ischemic heart disease