In vitro evaluation of motilin agonism by macrolide immunosuppressive drugs

Nephrology Dialysis Transplantation

Volumn 17, Issue 6, 2002, Pages 973-977

  Van Vlem, Bruno ^a   Schoonjans, Renaat ^a   Vanholder, Raymond ^a   De Vos, Martine ^a   Depoortere, Inge ^b   Peeters, Theo L ^b   Lefebvre, Romain ^c  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c GHENT UNIVERSITY   (Belgium)

Author keywords

Cyclosporin; Immunosuppressants; Macrolide; Motilin agonism; Sirolimus; Tacrolimus

Indexed keywords

CARBACHOL; CYCLOSPORIN; ERYTHROMYCIN LACTOBIONATE; HORMONE RECEPTOR; IMMUNOSUPPRESSIVE AGENT; MACROLIDE; MOTILIN; MOTILIN[13 LEUCINE]; RAPAMYCIN; TACROLIMUS; TETRODOTOXIN; ERYTHROMYCIN;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DUODENUM; ELECTRIC FIELD; ELECTROSTIMULATION; HOMOGENATE; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SMOOTH MUSCLE CONTRACTILITY; STOMACH ANTRUM; STOMACH EMPTYING; ANIMAL; DRUG EFFECT; DRUG POTENTIATION; KINETICS; MUSCLE CONTRACTION; PHYSIOLOGY; SMOOTH MUSCLE;

ANIMALS; CARBACHOL; CYCLOSPORINE; DUODENUM; ELECTRIC STIMULATION; ERYTHROMYCIN; IMMUNOSUPPRESSIVE AGENTS; KINETICS; MALE; MOTILIN; MUSCLE CONTRACTION; MUSCLE, SMOOTH; RABBITS; SIROLIMUS; TACROLIMUS;

EID: 0035991938     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/17.6.973     Document Type: Article

References (27)

1. Improved autonomic and gastric function in pancreas-kidney vs kidney-alone transplantation contributes to quality of life
2. Improvement in autonomic and gastric function following pancreas-kidney versus kidney-alone transplantation and the correlation with quality of life
3. Gastric emptying improvement after simultaneous segmental pancreas and kidney transplantation
4. Improvement of gastric emptying in diabetic gastroparesis by erythromycin. Preliminary studies
5. Erythromycin derivative improves gastric emptying and insulin requirement in diabetic patients with gastroparesis
6. Effects of a new motilide, ABT-229, on gastric emptying and postprandial antroduodenal motility in healthy volunteers
7. Erythromycin is a motilin receptor agonist
8. Differences in gastric motor activity in renal transplant recipients treated with FK-506 versus cyclosporine
9. Stimulatory effect of FK506 and erythromycin on pig intestinal motility
10. Erythromycin derivatives ABT 229 and GM 611 act on motilin receptors in the rabbit duodenum
11. EM574, an erythromycin derivative, is a motilin receptor agonist in the rabbit
12. Motilin receptors in rabbit stomach and small intestine
13. D-amino acid and alanine scan of porcine motilin
14. 13] motilin in the isolated rabbit gastric antrum
15. Motilin receptor: A model for development of prokinetics
16. Dosing and management guidelines for tacrolimus in renal transplant patients
17. Sirolimus in association with mycophenolate mofetil induction for the prevention of acute graft rejection in renal allograft recipients
18. Lake Louise Consensus Conference on cyclosporin monitoring in organ transplantation: Report of the consensus panel
19. Neuropeptide Y potentiates purinergic as well as adrenergic responses of the rabbit ear artery
20. Postjunctional synergism of noradrenaline and adenosine 5′-triphosphate in the mesenteric arterial bed of the rat
21. 2+ channels by FK506 in the porcine coronary artery
22. +)-channel activation and membrane hyperpolarization in bladder smooth muscle
23. Tacrolimus (FK506) modulates calcium release and contractility of intestinal smooth muscle
24. Does motilin stimulate the gastrointestinal motility of the pig? In vitro study using smooth muscle strips and dispersed muscle cells
25. Gastrokinetic effects of erythromycin: Myogenic and neurogenic mechanisms of action in rabbit stomach
26. Heterogeneity of motilin receptors in the gastrointestinal tract of the rabbit
27. Motilin receptors in the human antrum