Immunomodulatory and protective effects of moxifloxacin against Candida albicans-induced bronchopneumonia in mice injected with cyclophosphamide

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 8, 2002, Pages 2442-2449

  Shalit, Itamar ^a   Horev Azaria, Limor ^a   Fabian, Ina ^a   Blau, Hannah ^a   Kariv, Naam ^a   Shechtman, Itsak ^a   Alteraz, Hannah ^a   Kletter, Yehudith ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CEFTAZIDIME; CYCLOPHOSPHAMIDE; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 8; MOXIFLOXACIN; TUMOR NECROSIS FACTOR ALPHA; ANTIINFECTIVE AGENT; CEPHALOSPORIN DERIVATIVE; HETEROCYCLIC COMPOUND; PROTEIN SYNTHESIS INHIBITOR; QUINOLINE DERIVATIVE; QUINOLONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFUNGAL ACTIVITY; ARTICLE; BRONCHOPNEUMONIA; CANDIDA ALBICANS; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG ACTIVITY; DRUG EFFECT; HISTOPATHOLOGY; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; INOCULATION; LUNG HOMOGENATE; MALE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; WEIGHT REDUCTION; ANIMAL; BAGG ALBINO MOUSE; BODY WEIGHT; CANDIDIASIS; LUNG; METABOLISM; MICROBIOLOGY; NEUTROPENIA; PATHOLOGY; SURVIVAL;

ANIMAL; ANTI-INFECTIVE AGENTS, FLUOROQUINOLONE; BODY WEIGHT; BRONCHOPNEUMONIA; CANDIDIASIS; CEFTAZIDIME; CEPHALOSPORINS; CYCLOPHOSPHAMIDE; CYTOKINES; LUNG; MALE; MICE; MICE, INBRED BALB C; NEUTROPENIA; PROTEIN SYNTHESIS INHIBITORS; SURVIVAL; ANIMALS; ANTI-INFECTIVE AGENTS; AZA COMPOUNDS; FLUOROQUINOLONES; QUINOLINES;

EID: 0035991839     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.8.2442-2449.2002     Document Type: Article

References (28)

1. Induction of tumor necrosis factor-alpha in murine Candida albicans infection
2. Effects of quinolones on tumor necrosis factor production by human monocytes
3. Ciprofloxacin immunomodulation of experimental antiphospholipid syndrome associated with elevation of interleukin-3 and granulocyte-macrophage colony-stimulating factor expression
4. Candida albicans induces the release of inflammatory mediators from human peripheral blood monocytes
5. Candida albicans trigger interleukin-6 and interleukin-8 responses by oral fibroblasts in vitro
6. A double-blind comparison of empirical oral and intravenous antibiotic therapy for low-risk febrile patients with neutropenia during cancer chemotherapy
7. Production of tumor necrosis factor-alpha in granulocytopenic mice with pulmonary candidiasis and its modification with granulocyte colony-stimulating factor
8. Fluoroquinolone antimicrobial agents
9. Expression of macrophage inflammatory protein-2 and KC mRNA in pulmonary inflammation
10. Quinolactacins A, B, and C: Novel quinolone compounds from Penicillium sp. EPF-6. I. Taxonomy, production, isolation and biological properties
11. Effects of interleukin-10 on chemokine KC gene expression by mouse peritoneal macrophages in response to Candida albicans
12. Inhibition of lipid peroxidation, NF-activation and IL-8 production by rebamipide in Helicobacter pyloristimulated gastric epithelial cells
13. Enhanced repopulation of murine hematopoietic organs in sublethally irradiated mice after treatment with ciprofloxacin
14. Recombinant GM-CSF reduces lung injury and mortality during neutropenic Candida sepsis
15. Mechanisms of the proinflammatory response of endothelial cells to Candida albicans infection
16. The effect of three broad-spectrum antimicrobials on mononuclear cell responses to encapsulated bacteria: Evidence for downregulation of cytokine mRNA transcription by trovafloxacin
17. Increased interleukin 2 transcription in murine lymphocytes by ciprofloxacin
18. Surfactant protein A downregulates proinflammatory cytokine production evoked by Candida albicans in human alveolar macrophages and monocytes
19. Effect of the quinolones on the immune system
20. Enhanced hematopoiesis in sublethally irradiated mice treated with various quinolones
21. Immunology effects of moxifloxacin in comparison to ciprofloxacin and G-CSF in a murine model of cyclophosphamide-induced leukopenia
22. Effect of ciprofloxacin and pefloxacin on bone marrow engraftment in the spleen of mice
23. Early onset cyclophosphamide-induced interstitial pneumonitis
24. Inhibitory activities of gatifloxacin (AM-1155), a newly developed fluoroquinolone, against bacterial and mammalian type II topoisomerases
25. Responsiveness of human polymorphonuclear cells (PMNL) to stimulation by a mannoprotein fraction (MP-F2) of Candida albicans: Enhanced production of IL-6 and tumour necrosis factor-alpha (TNF-α) by MP-F2-stimulated PMNL from HIV-infected subjects
26. Differential chemokine response of human monocytes to yeast and hyphal forms of Candida albicans and its relation to the β-1,6 glucan of the fungal cell wall
27. Interleukin 8 in serum in granulocytopenic patients with infections
28. Involvement of mannose receptor in cytokine interleukin-1β (IL-1β), IL-6, and granulocyte-macrophage colony-stimulating factor responses, but not in chemokine macrophage inflammatory protein 1β (MIP-1β), MIP-2, and KC responses, caused by attachment of Candida albicans to macrophages