Intrapericardial therapeutics: A pharmacodynamic and pharmacokinetic comparison between pericardial and intravenous procainamide delivery

Journal of Cardiovascular Electrophysiology

Volumn 13, Issue 6, 2002, Pages 605-611

  Ujhelyi, Michael R ^a,b   Hadsall, Kelly Z ^b   Euler, David E ^a   Mehra, Rahul ^a  

^a MEDTRONIC INC   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Antiarrhythmic therapy; Atrial fibrillation; Conduction velocity; Electrophysiology; Pericardium; Pharmacokinetics; Procainamide; Refractory period; Ventricular fibrillation

Indexed keywords

PROCAINAMIDE; CARDIOVASCULAR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTICLE; ATRIOVENTRICULAR CONDUCTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; HEART ATRIUM FIBRILLATION; HEART ELECTROPHYSIOLOGY; NONHUMAN; PERICARDIUM; PRIORITY JOURNAL; SWINE; ACTION POTENTIAL; ANIMAL; BIOLOGICAL MODEL; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECT; DRUG INSTILLATION; HEART ATRIUM; HEART FUNCTION TEST; HEART MUSCLE CONDUCTION SYSTEM; HEART VENTRICLE; HEART VENTRICLE FIBRILLATION; NERVE CONDUCTION; PATHOLOGY; TREATMENT OUTCOME;

ACTION POTENTIALS; ANIMALS; ATRIAL FIBRILLATION; CARDIOVASCULAR AGENTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; HEART ATRIA; HEART CONDUCTION SYSTEM; HEART VENTRICLES; INSTILLATION, DRUG; MODELS, CARDIOVASCULAR; PERICARDIUM; PROCAINAMIDE; REFRACTORY PERIOD, ELECTROPHYSIOLOGICAL; SWINE; TREATMENT OUTCOME; VENTRICULAR FIBRILLATION;

EID: 0035991617     PISSN: 10453873     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1540-8167.2002.00605.x     Document Type: Article

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